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Pulmonary sclerosing pneumocytoma presenting a peritumoral halo and an intervening lucent zone on computed tomography: Radiology–pathology correlation

机译:患有Peritumoral光环的肺硬化的肺细胞瘤和在计算机断层扫描的一个介入朗讯区:放射学 - 病理学相关性

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A 56-year-old woman presented with blood-tinged sputum. A chest radiograph showed a nodule in the rightmid-lung zone. Chest computed tomography (CT) revealeda 1.6 cm well-demarcated nodule with eccentric calcification in the right middle lobe (Fig 1a). The lung windowsetting showed ground glass opacity (GGO) surroundingthe nodule, creating a halo sign (Fig 1b). An interveninglucent area between the nodule and GGO was also noted.The nodule was suspected as being benign (e.g. ahamartoma); however, associated findings, such as GGOand peritumoral lucent components, could not beexplained. On 2-[fluorine 18]fluoro-2-deoxy-D-glucose(FDG) positron emission tomography/CT, the nodule andGGO showed mild FDG uptake (maximum standardizeduptake value 1.7–2.0). The possibility of malignancy showing lepidic growth could not be excluded. Thus, a rightmiddle lobectomy was performed. Histopathological analysis revealed a well-circumscribed tumor with abundanthemorrhage. The tumor was composed of pneumocytesand round cells, suggesting pulmonary sclerosingpneumocytoma (PSP) (Fig 2a). TTF-1 and vimentin werepositive on immunohistochemical staining. The halo signon CT was correlated with hemorrhage in the lung.
机译:一个56岁的女子患有血腥的痰。胸部Xchargraph在右下肺区显示出结节。胸部计算断层扫描(CT)显示1.6cm偏向的结节,右侧叶中偏心钙化(图1A)。肺部窗扇显示出围绕结节的覆盖玻璃不透明度(ggo),创造光环符号(图1B)。还注意到结节和ggo之间的介入薄解区域。结节被怀疑是良性的(例如Ahamartoma);然而,相关的发现,例如GGOAND Peritumoral朗讯组分,不能缺乏缺乏。在2- [氟18]氟-2-脱氧-D-葡萄糖(FDG)正电子发射断层扫描/ CT,结节Andggo显示出轻度FDG吸收(最大标准化值1.7-2.0)。没有排除含有Lepidic生长的恶性肿瘤的可能性。因此,进行了右肌曲霉素。组织病理学分析揭示了一种具有丰富的粗糙肿瘤。肿瘤由肺细胞细胞和圆形细胞组成,表明肺硬质性细胞瘤(PSP)(图2A)。 TTF-1和Vimentin呈免疫组化染色。 Halo Signon CT与肺中的出血相关。

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