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首页> 外文期刊>Journal of Behavioral and Brain Science >Changes in the Brain’s Intrinsic Organization in the Resting State with Real-Time fMRI Neurofeedback Training of Posterior Cingulate Cortex Activity
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Changes in the Brain’s Intrinsic Organization in the Resting State with Real-Time fMRI Neurofeedback Training of Posterior Cingulate Cortex Activity

机译：大脑内在组织在静止状态下的变化，具有实时FMRI神经融合训练后刺的皮质活动

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Real-time functional magnetic resonance imaging (rtfMRI) technology has been widely used to train subjects to actively regulate the activity of specific brain regions. Although many previous studies have demonstrated that neurofeedback training alters the functional connectivity between brain regions in the task state and resting state, it is unclear how the regulation of the key hub of the default mode network (DMN) affects the topological properties of the resting-state brain network. The current study aimed to investigate what topological changes would occur in the large-scale intrinsic organization of the resting state after the real-time down-regulation of the posterior cingulate cortex (PCC). The results indicated that the down-regulation of the PCC in the DMN reduced the functional connectivity of the PCC with the nodes outside of the DMN and reduced functional connectivity between the superior medial frontal gyrus (SFGmed) and parahippocampal gyrus (PHG) in the experimental group. Moreover, the nodal graph properties of the SFGmed were reduced, while that of the PHG showed the opposite alteration after the down-regulation of the PCC. These findings possibly suggest that the regulation of the key hub of the DMN, the PCC, mainly changed the information transfer of the SFGmed and PHG.
机译：实时功能磁共振成像（RTFMRI）技术已广泛用于培训受试者，积极调节特定脑区的活动。虽然以前的许多研究表明，神经融合训练在任务状态和休息状态下大脑区域之间的功能连接，但目前尚不清楚默认模式网络（DMN）的关键中心的调节如何影响静止的拓扑属性 - 国家大脑网络。目前的研究旨在调查在后铰接皮质（PCC）的实时下调后静息状态的大规模内在组织中发生的拓扑变化。结果表明，DMN中PCC的下调降低了PCC与DMN之外的节点的功能连通性，并在实验中减少了上内侧前转位（SFGMED）和PLAHIPPocampal（PHG）之间的功能连通性团体。此外，SFGMED的节点图性能降低，而PHG的节点曲线结构表明，PCC对下调后的相反变化。这些发现可能表明，DMN的关键中心的调节，PCC，主要改变了SFGMED和PHG的信息传递。

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