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Surveying the Effect of Opioid Abuse on the Extent of Coronary Artery Diseases in Diabetic Patients

机译：对糖尿病患者冠状动脉疾病程度的调查造成阿片类药物的影响

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Background. Diabetes mellitus is recognized as one of the most common, serious, and costly chronic diseases. Opium addiction is also a common health problem in Iran. Given the high prevalence of opium use in South Khorasan Province and the increasing prevalence of opioid abuse in the community, this study was performed to investigate the effect of opioid abuse on the extent of disease in diabetic patients undergoing coronary angiography in the cardiology department of Vali-e-Asr Hospital in Birjand city, South Khorasan Province, Iran. Methods. This study recruited a total of 1051 diabetic patients who underwent coronary angiography in the cardiology department of Vali-e-Asr Hospital of Birjand city from 2011 to 2015. The collected data were analyzed using SPSS version 22.0 with the chi-square test and univariate regression analysis. P value 0.05 was considered as statistically significant. Results. Among opiate-addicted diabetics, the risk of coronary artery disease was 0.44 times higher than among nonaddicted diabetics (range 0.24–0.77, P=0.004). The extent of coronary vessel involvement, when present, was not different between the two groups. Conclusion. Opiate-addicted diabetics appear to be more susceptible to CAD than their nonaddicted counterparts. The determinants and correlates of this interaction must be the subject of further study.
机译：背景。糖尿病被认为是最常见，严重和昂贵的慢性疾病之一。鸦片成瘾也是伊朗的常见健康问题。鉴于南高卢山省鸦片利用的普及率高，对社区中阿片类药物滥用的普遍普照普遍存在，该研究进行了探讨阿片类药物滥用血管学患者血管科血管科患者疾病程度的影响-e-asr医院在伊朗南霍罗桑省Birjand市。方法。本研究招募了来自2011年至2015年Birjand City Vali-e-Asr医院Vali-E-Asr Hospital的心脏病学系冠状动脉学系患者的1051名糖尿病患者。使用SPSS版本22.0与Chi-Square测试和单变量回归分析了收集的数据分析。 P值<0.05被认为是统计学上显着的。结果。在阿片类糖尿病患者中，冠状动脉疾病的风险比非新糖尿病患者高0.44倍（范围0.24-0.77，p = 0.004）。当存在时，冠状动脉血管受累的程度在两组之间没有差异。结论。阿片类药物上瘾的糖尿病患者似乎比他们的非新的同行更容易受到CAD的影响。这种相互作用的决定因素必须是进一步研究的主题。

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