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首页> 外文期刊>Diabetes care >Relationship between carotid intima-media thickness and the presence and extent of coronary stenosis in type 2 diabetic patients with carotid atherosclerosis but without history of coronary artery disease.
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Relationship between carotid intima-media thickness and the presence and extent of coronary stenosis in type 2 diabetic patients with carotid atherosclerosis but without history of coronary artery disease.

机译：2型糖尿病伴颈动脉粥样硬化但无冠心病史的糖尿病患者颈动脉内膜中层厚度与冠状动脉狭窄的存在和程度之间的关系。

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OBJECTIVE: We examined the relationship between the presence and extent of coronary stenosis and carotid intima-media thickness (CIMT) in type 2 diabetic patients without history of coronary artery disease (CAD) but with carotid atherosclerosis. RESEARCH DESIGN AND METHODS: A total of 91 type 2 diabetic patients underwent multi-slice computed tomography coronary angiography. RESULTS: Max-IMT in the >/= 50% stenosis group by multi-slice computed tomography coronary angiography estimation was significantly greater than the 0-25 and 25-50% stenosis group (2.68 +/- 0.77 vs. 1.61 +/- 0.49 mm, P < 0.0005, and 2.14 +/- 0.81 mm, P < 0.05, respectively), and max-IMT in the 25-50% stenosis group was significantly greater than the 0-25% stenosis group (P < 0.05) after adjustment for age, sex, duration of type 2 diabetes, hypertension, and dyslipidemia. In the analysis for trend through the categories of max-IMT, as max-IMT increased, the percentage of >/= 50% stenosis increased and the percentage of 0-25% stenosis decreased. CONCLUSIONS: Our data suggest that max-IMT might be closely associated with the extent of coronary stenosis in type 2 diabetic patients without history of CAD but with carotid atherosclerosis.
机译：目的：我们研究了2型糖尿病无冠心病（CAD）但有颈动脉粥样硬化的2型糖尿病患者中冠状动脉狭窄的存在和程度与颈动脉内中膜厚度（CIMT）的关系。研究设计和方法：总共91例2型糖尿病患者接受了多层计算机断层扫描冠状动脉造影。结果：多层计算机断层扫描冠状动脉造影估计> / = 50％狭窄组的Max-IMT显着大于0-25和25-50％狭窄组（2.68 +/- 0.77对1.61 +/- 25-50％狭窄组的最大IMT分别为0.49 mm，P <0.0005和2.14 +/- 0.81 mm，P <0.05）和max-IMT显着大于0-25％狭窄组（P <0.05）调整年龄，性别，2型糖尿病病程，高血压和血脂异常后。在通过最大IMT类别进行的趋势分析中，随着最大IMT的增加，> / = 50％狭窄的百分比增加，而0-25％狭窄的百分比减少。结论：我们的数据表明，max-IMT可能与2型糖尿病患者无冠心病但伴有颈动脉粥样硬化的冠状动脉狭窄程度密切相关。

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