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Clinical Significance of Low-Flow Time in Patients Undergoing Extracorporeal Cardiopulmonary Resuscitation: Results from the RESCUE Registry

机译:低流量时间在接受体外心肺复苏的患者中的临床意义:救援登记处的结果

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Limited data are available on the association between low-flow time and survival in patients with in-hospital cardiac arrest (IHCA) who undergo extracorporeal cardiopulmonary resuscitation (ECPR). We evaluated data from 183 IHCA patients who underwent ECPR as a rescue procedure. Patients were divided into two groups: patients undergoing extracorporeal membrane oxygenation as an adjunct to standard cardiopulmonary resuscitation for less than 38 min ( n = 110) or for longer than 38 min ( n = 73). The ECPR ≤ 38 min group had a significantly greater incidence of survival to discharge compared to the ECPR 38 min group (40.0% versus 24.7%, p = 0.032). The incidence of good neurologic outcomes at discharge tended to be greater in the ECPR ≤ 38 min group than in the ECPR 38 min group (35.5% versus 24.7%, p = 0.102). The incidences of limb ischemia ( p = 0.354) and stroke ( p = 0.805) were similar between the two groups, but major bleeding occurred less frequently in the ECPR ≤ 38 min group compared to the ECPR 38 min group ( p = 0.002). Low-flow time ≤ 38 min may reduce the risk of mortality and fatal neurologic damage and could be a measure of optimal management in patients with IHCA.
机译:有限的数据可以在医院内心脏骤停(IHCA)的患者中低流量时间和生存之间的关联,受到体外心肺复苏(ECPR)。我们评估了183名IHCA患者作为救援程序的IHCA患者的数据。患者分为两组:经过体外膜氧合的患者作为标准心肺重新刺除的辅助含量小于38分钟(n = 110)或超过38分钟(n = 73)。与ECPR> 38 min组相比,ECPR≤38min组对放电的生存发生率显着更大(40.0%,P = 0.032)。在ECPR≤38min组中,放电良好神经系统结果的发生率趋于更大,而不是ECPR> 38 min组(35.5%而24.7%,p = 0.102)。两组之间的肢体缺血(P = 0.354)和中风(P = 0.805)相似,但与ECPR> 38 min组相比,ECPR≤38min组的重大出血均不太频繁出血(P = 0.002) 。低流量时间≤38分钟可降低死亡率和致命神经系统损伤的风险,并且可以是IHCA患者最佳管理的量度。

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