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Notching and Pulsatility Index of the Uterine Arteries and Preeclampsia in Twin Pregnancies

机译:子宫动脉和术前胰腺癌的痰和脉动性指数

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Increased uterine artery Doppler indices have been shown to be associated with preeclampsia and adverse pregnancy outcomes in singleton and twin pregnancies. At 20–22 weeks of gestation, we assessed the use of notching, the highest, lowest, and mean pulsatility index (PI), and the combination of notching and PI of the uterine arteries to screen for preeclampsia. This was done in a cohort of 380 twin pregnancies. The results showed that the combination of notching and the highest PI above the 95th centile of the uterine arteries gives the best screening characteristics for preeclampsia in twin pregnancies. We calculated sensitivities for preeclampsia for notching, highest PI, and the combination of notching and the highest PI of 50%, 45% and 91%, with specificities of 96%, 96% and 93%, respectively. The present findings demonstrate that notching, increased highest PI, and the combination of notching and the highest PI of the uterine arteries is associated with an increased risk of preeclampsia in twin pregnancies. We observed the highest sensitivity and specificity by using the combination of notching and the highest PI of the uterine arteries.
机译:增加子宫动脉多普勒指数已显示与单身和单身妊娠的先兆子痫和不良妊娠结果有关。在妊娠的20-22周,我们评估了使用缺口,最低,最低和平均脉动指数(PI)的使用,以及子宫动脉的缺口和PI的组合,以筛选出胰岛素。这是在380个双胞胎怀孕的队列中完成的。结果表明,上述缺口和最高PI的组合,子宫动脉的第95升纤维中均为双胞胎妊娠的先兆子痫筛选特征。我们计算出缺口,最高PI的预胰抗,最高PI和50%,45%和91%的组合,分别为96%,96%和93%的特异性。本研究结果表明,缺口,增加的最高PI和缺口和子宫动脉最高PI的组合与单人妊娠中预痫的风险增加有关。我们通过使用凹口和子宫动脉的最高PI的组合来观察到最高的敏感性和特异性。

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