• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Clinical Medicine >Bilateral Subthalamic Nucleus Deep Brain Stimulation under General Anesthesia: Literature Review and Single Center Experience
【24h】

Bilateral Subthalamic Nucleus Deep Brain Stimulation under General Anesthesia: Literature Review and Single Center Experience

机译：一般麻醉下双侧次粒细胞核深脑刺激：文献综述和单中心经验

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Bilateral subthalamic nucleus (STN) Deep brain stimulation (DBS) is a well-established treatment in patients with Parkinson’s disease (PD). Traditionally, STN DBS for PD is performed by using microelectrode recording (MER) and/or intraoperative macrostimulation under local anesthesia (LA). However, many patients cannot tolerate the long operation time under LA without medication. In addition, it cannot be even be performed on PD patients with poor physical and neurological condition. Recently, it has been reported that STN DBS under general anesthesia (GA) can be successfully performed due to the feasible MER under GA, as well as the technical advancement in direct targeting and intraoperative imaging. The authors reviewed the previously published literature on STN DBS under GA using intraoperative imaging and MER, focused on discussing the technique, clinical outcome, and the complication, as well as introducing our single-center experience. Based on the reports of previously published studies and ours, GA did not interfere with the MER signal from STN. STN DBS under GA without intraoperative stimulation shows similar or better clinical outcome without any additional complication compared to STN DBS under LA. Long-term follow-up with a large number of the patients would be necessary to validate the safety and efficacy of STN DBS under GA.
机译：双侧次粒细胞核（STN）深脑刺激（DBS）是帕金森病（PD）患者的良好治疗方法。传统上，通过在局部麻醉（LA）下使用微电极记录（MER）和/或术中癌刺激来执行STN DBS。然而，许多患者在没有药物的情况下不能忍受LA下的长操作时间。此外，甚至不能对具有差的物理和神经功能差的PD患者进行。最近，据报道，由于GA下的可行性MER，可以成功地执行全身麻醉（GA）下的STN DB，以及直接靶向和术中成像的技术进步。作者使用术中的成像和MER，专注于讨论技术，临床结果和复杂性，以及引入我们的单中心体验，审查了在GA下的STN DBS上的先前发表的文献。根据先前公布的研究和我们的报告，GA没有干扰来自STN的MER信号。在没有术中刺激的GA下的STN DBS显示出类似或更高的临床结果，而LA下的STN DBS相比，没有任何额外的复杂性。对于大量患者的长期随访是必要的，以验证STN DBS在GA下的安全性和功效。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号