...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Clinical Medicine Research >Accuracy of Unstimulated Basal Serum Thyroglobulin Levels in Assessing the Completeness of Thyroidectomy
【24h】

Accuracy of Unstimulated Basal Serum Thyroglobulin Levels in Assessing the Completeness of Thyroidectomy

机译：非刺激基础血清甲状腺素水平评估甲状腺切除术的完整性的准确性

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background: Complete excision is important for proper surgical treatment of thyroid disorders. Functional thyroid tissue can be identified based on the level of serum thyroglobulin (Tg), which is produced only by the thyroid follicular cells, and nuclear scan. Methods: Serum thyroid stimulating hormone (TSH), free thyroxin (FT4), basal (unstimulated) Tg and anti-Tg antibody (anti-Tg ab) were measured at the sixth postoperative month in 100 patients with benign thyroid disorders treated by total thyroidectomy. Thyroid nuclear scan was obtained to identify functional remnant of the thyroid gland. The sensitivity, specificity, accuracy, positive predictive value (PPV) and negative predictive value (NPV) of the Tg levels in assessing thyroid remnant were calculated. Results: Positive scan showed thyroid remnant in 23 patients, among whom 16 were Tg positive (true positive) and seven were Tg negative ( 0.5 ng/mL) level accurately indicated the functional thyroid remnant after total thyroidectomy. The negative Tg (< 0.5 ng/mL) level supported complete excision of the thyroid gland. The surgical completeness of total thyroidectomy was accurately evaluated based on the serum Tg levels. Therefore, serum Tg levels should be measured in postoperative follow-up to determine the completeness of total thyroidectomy.J Clin Med Res. 2014;6(5):369-373doi: http://dx.doi.org/10.14740/jocmr1873w
机译：背景：完全切除对甲状腺疾病的适当手术治疗非常重要。可以基于血清甲状腺素（Tg）的水平来鉴定功能性甲状腺组织，其仅由甲状腺滤泡细胞和核扫描产生。方法：血清甲状腺刺激激素（TSH），游离甲状腺素（FT4），基础（未刺激的）TG和抗TG抗体（抗TG AB）在通过总甲状腺切除术治疗的100名良性甲状腺疾病患者中，测量了六期。获得甲状腺核扫描以鉴定甲状腺的功能残余物。计算了评估甲状腺残余的TG水平的敏感性，特异性，准确度，阳性预测值（PPV）和负预测值（NPV）。结果：阳性扫描在23例患者中显示甲状腺残余物，其中16个是Tg阳性（真正的阳性），7例为Tg阴性（0.5ng / ml）水平，精确指示总甲状腺切除术后的功能性甲状腺残余物。负Tg（<0.5ng / ml）水平支持甲状腺的完全切除。基于血清TG水平准确地评估总甲状腺切除术的手术完整性。因此，血清TG水平应在术后随访中测量以确定总甲状腺切除术的完整性.J Clin Med Res。 2014; 6（5）：369-373DOI：http：//dx.doi.org/10.14740/jocmr1873w

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号