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首页> 外文期刊>Journal of Clinical Medicine Research >The Ratio of Low-Frequency to High-Frequency in Ambulatory Electrocardiographic Monitoring Immediately Before Coronary Angiography as a Predictor of the Presence of Coronary Artery Disease
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The Ratio of Low-Frequency to High-Frequency in Ambulatory Electrocardiographic Monitoring Immediately Before Coronary Angiography as a Predictor of the Presence of Coronary Artery Disease

机译:在冠状动脉血管造影之前,低频与高频与高频的比率,冠状动脉造影以冠状动脉疾病存在的预测因子

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Background: There is considerable evidence that impaired autonomic control may be associated with the etiology of coronary artery disease (CAD). We hypothesized that the autonomic imbalance as assessed by measuring heart rate variability (HRV) and biological parameters before and after coronary angiography (CAG) may predict the presence of CAD. Methods: Ambulatory electrocardiographic (ECG) examination using eHEART? (Parama-Tec) is a novel, rapid, and simple method with which we can measure HRV within 5 min. We selected patients (n = 78, 68 ± 10 y) who underwent CAG and analyzed their ambulatory ECGs and blood levels of neuropeptides at both 1 day and immediately before and after CAG. The patients were divided into the presence (n = 64, CAD group) and absence of CAD (n = 14, non-CAD group). Results: Although the CAD group showed an increase in blood pressure immediately before CAG, the ratio of low-frequency to high-frequency (LF/HF) was significantly decreased in the CAD group, but not in the non-CAD group. On the other hand, there was no difference in a coefficient of variation of the R-R interval or pulse rate between the two groups. CAD was independently associated with hypertension (P = 0.011), dyslipidemia (P = 0.009), and LF/HF immediately before CAG (P = 0.046) by a logistic regression analysis. Conclusions: These findings suggest that LF/HF immediately before CAG in addition to hypertension and dyslipidemia might predict the presence of CAD.J Clin Med Res. 2014;6(1):36-43doi: http://dx.doi.org/10.4021/jocmr1661w
机译:背景:具有相当大的证据表明自主检测可能与冠状动脉疾病(CAD)的病因有关。我们假设通过测量心率变异性(HRV)和冠状动脉造影前后的生物参数(CAG)之前和生物参数评估的自主失衡可以预测CAD的存在。方法:使用eheart的动态心电图(ECG)检查吗? (parama-tec)是一种新颖,快速,简单的方法,我们可以在5分钟内测量HRV。我们选择了患者(n = 78,68±10 y),他经历了CAG,并在1天内分析了它们的动态ECG和血液水平,并在CAG之前和之后立即进行了分析。将患者分为存在(n = 64,CAD组),并且不存在CAD(n = 14,非CAD组)。结果:虽然CAD组在CAG之前立即显示出血压的增加,但CAD组低频率与高频(LF / HF)的比例显着降低,但不在非CAD组中显着降低。另一方面,在两组之间的R-R间隔或脉冲速率的变化系数没有差异。通过逻辑回归分析,CAD独立地与高血压(P = 0.011),血脂血症(P = 0.016)和LF / HF相关联。结论:这些发现表明,除了高血压和血脂异常外,CAG外立即的LF / HF可能预测CAD.J Clin Med Res的存在。 2014; 6(1):36-43DOI:http://dx.doi.org/10.4021/jocmr1661w

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