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首页> 外文期刊>Journal of Clinical Medicine Research >Overprescribed Medications for US Adults: Four Major Examples
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Overprescribed Medications for US Adults: Four Major Examples

机译：美国成年人过度归档药物：四个主要例子

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To understand possible medication overprescribing, it would be important to know which classes are the most prescribed, for which indications, for what duration, and for which age groups. Among the 10 most frequently prescribed medication classes for US adults, four were evaluated for overprescribing, and systematically assessed in relation to their primary indication. The assessment included usage patterns, trends, age of recipients, treatment duration, and benefits versus adverse consequences. The findings in this selective review are supported by an extensive search of the medical literature. The four selected medication categories and their most common indication included opioids for chronic pain, proton pump inhibitors for indigestion, levothyroxine for subclinical hypothyroidism, and antidepressants for subsyndromal levels of depression. These medications, grouped by their most frequent indication along with polypharmacy, have experienced major prescription increases in recent years, particularly among older patients. Most concerning is that they have been frequently prescribed for extended periods, usually with inadequate evidence of benefit. High drug usage patterns can aid in quantifying overprescribing within polypharmacy by age group.
机译：为了了解可能的药物过度规范，重要的是要知道哪些课程是最规定的，适用于哪些持续时间，以及哪些年龄组。在美国成年人的10级最常见的10个规定的药物课中，评估了四个过度刻度，并系统地评估了他们的主要指示。评估包括使用模式，趋势，接受者年龄，治疗持续时间和益处与不良后果。这种选择评论中的调查结果得到了对医学文献的广泛寻求支持。四种选定的药物类别及其最常见的指示包括慢性疼痛的阿片类药物，用于消化不良的质子泵抑制剂，亚临床甲状腺功能减退症的左甲磺酮，以及用于抑郁症的抗抑郁药。这些药物由他们最常见的迹象组成，近年来经历了近年来的主要处方增加，特别是老年患者。大多数人的涉及是他们经常在延长的时间内进行规定，通常具有不足的益处证据。高药物使用模式可以帮助量化年龄组在多酚省内内的过度折叠。

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