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首页> 外文期刊>Journal of Clinical Medicine Research >A Scoping Review on Clinical Trials of Pain Reduction With Cannabis Administration in Adults
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A Scoping Review on Clinical Trials of Pain Reduction With Cannabis Administration in Adults

机译：关于成人大麻诊断临床试验的范围

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Indications of cannabis use are numerous although the indication to relief pain remains a major research interest and clinical application. Studies investigating the effect of herbal cannabis and cannabis-based medicine on neuropathic, non-neuropathic pain, acute pain and experimentally induced pain were reviewed. A search was performed in PubMed and Cochrane library for articles published in English between January 1, 2000 and May 8, 2020. The search terms used were related to cannabis and pain in adults. We identified 34 studies, of which 30 were randomized controlled clinical trials (RCTs). Varying effects were identified from the RCTs, and as expected more promising effects from non-RCTs. Cannabis-based medications were found most effective as an adjuvant therapy in refractory multiple sclerosis, and weak evidence was found to support the treatment of cancer pain especially in advanced stages. Chronic rheumatic pain showed promising results. Adverse events of cannabis-based treatment were found to be more frequent with tetrahydrocannabinol herbal strains compared to other cannabis-derived products.Copyright 2020, Haleem et al.
机译：大麻使用的指示许多虽然浮雕疼痛的指示仍然是一个主要的研究兴趣和临床应用。研究了研究草药大麻和基于大麻药物对神经性，非神经病疼痛，急性疼痛和实验诱导的疼痛的影响。在2000年1月1日至5月8日之间以英语发布的文章在PubMed和Cochrane库中进行了搜索。使用的搜索条件与大麻和成人疼痛有关。我们确定了34项研究，其中30项是随机对照临床试验（RCT）。从RCT鉴定不同效果，并且随着非RCT的预期更具前景的影响。基于大麻的药物被认为是难治性多发性硬化症中的佐剂治疗最有效的，并且发现弱的证据支持癌症疼痛，特别是在高级阶段。慢性风湿性疼痛显示出有前途的结果。与其他大麻衍生的产品相比，发现基于大麻的治疗的不良事件是更频繁的。与其他大麻衍生的产品相比，柔小菌衍生的产物。柔浦2020，Haleem等人。

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