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Neoplasms of the appendix: An experience of a tertiary hospital in Southwestern Nigeria

机译:附录的肿瘤:尼日利亚西南部一家高等医院的经验

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Background: The appendix is a vestigial tube-like organ. Its exact physiological function is unknown. Appendectomies are done usually following a clinical diagnosis of acute appendicitis. Neoplasms can arise from this organ as well. Carcinoids are the most common neoplasms arising commonly at the tips. This retrospective review of neoplasms of the appendix was aimed at identifying the incidence and describing the histological variants of neoplasms of the appendix in our environment. Materials and Methods: This study was a 10-year retrospective review of all appendectomy specimens submitted to the Department of Pathology, University College Hospital, Ibadan, Nigeria, from January 1, 2009, to December 31, 2018. Microscopy was done examining the longitudinal sections from the tip to the base of the appendix. The histological diagnosis was extracted from the records in the department and classified using the WHO classification of tumors of the appendix (2019). Patients' biodata such as age and sex were also extracted. The data were analyzed for frequency distribution using SPSS 23. Results: The incidence of neoplasms in the appendix was 0.84% of the 1071 appendectomies received in our department over the study period. Low-grade appendiceal mucinous neoplasm (LAMN) was the most common histological variant accounting for 55.5% of neoplasms, followed by metastatic carcinoma at 22.2% and carcinoids at 11.1%. There was a female preponderance of 77.8%. Conclusion: Neoplasms of the appendix are rare in our environment, and LAMN was the most common neoplasm of the appendix in our institution. There is a female preponderance among patients with appendiceal neoplasms.
机译:背景:附录是一种类似于类的管器官。它确实的生理功能未知。阑尾切除术通常在急性阑尾炎的临床诊断之后进行。肿瘤也可以从这个器官出现。 CARCINOIDS是最常见的肿瘤,通常是在提示处产生的。该回顾性审查附录的肿瘤旨在鉴定该发病率,并描述了我们环境中附录的肿瘤的组织学变体。材料和方法:本研究是对提交的所有阑尾切除术标本,大学学院医院,尼日利亚,2009年1月1日至2018年12月31日,对尼日利亚大学医院的所有阑尾切除术标本进行了10年的回顾述评。[Microscopy是否完成了纵向从尖端到附录基础的部分。组织学诊断是从部门的记录中提取,并使用申请肿瘤分类进行分类(2019)。还提取了患者的生物数据,如年龄和性别。通过SPSS 23分析数据进行频率分布。结果:在研究期间,附录中肿瘤的发病率为1071个阑尾切除术的0.84%。低级阑尾粘液瘤状肿瘤(LAMN)是最常见的组织学变体占55.5%的肿瘤,其次是22.2%的转移性癌,癌为11.1%。女性优势77.8%。结论:阑尾的肿瘤在我们的环境中是罕见的,而Lamn是我们机构中最常见的阑尾最常见的肿瘤。阑尾肿瘤患者存在女性优势。

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