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首页> 外文期刊>Journal of International Medical Research >The Incidence of Postoperative Nausea and Vomiting after Thyroidectomy using Three Anaesthetic Techniques
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The Incidence of Postoperative Nausea and Vomiting after Thyroidectomy using Three Anaesthetic Techniques

机译：使用三种麻醉技术术后恶心术后恶心和呕吐的发生率

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摘要

The choice of anaesthetics can affect the incidence of postoperative nausea and vomiting (PONV). This study compared the incidence of PONV in 177 female patients who underwent thyroidectomy, with anaesthesia induced and maintained using one of three regimens: (i) sevoflurane (thiopental sodium 4–5 mg/kg and sevoflurane 2.0–2.5 vol% in 50% air); (ii) total intravenous anaesthesia (TIVA; propofol-remifentanil [target blood concentrations 2.5–3.5 μg/ml and 3.5–4.5 ng/ml, respectively]); or (iii) combined inhalation and intravenous anaesthesia (sevoflurane 1.0 vol% in 50% air plus propofol-remifentanil [target blood concentrations 1.5–2.5 μg/ml and 2.5–3.5 ng/ml, respectively]). The incidence and severity of PONV and the need for rescue antiemetics were assessed at 0–24 h postoperatively. Overall, the incidence of PONV was significantly lower in the TIVA and combined groups compared with the sevoflurane group (33.9%, 39.0% and 64.4%, respectively). In conclusion, the maintenance of anaesthesia with propofol-remifentanil or sevoflurane-propofol-remifentanil decreased the incidence of PONV compared with sevoflurane alone.
机译：麻醉剂的选择可以影响术后恶心和呕吐（PONV）的发生率。本研究比较了177名雌性患者的PONV发病率，所述患者接受甲状腺切除术的患者，使用三个方案中的一种感应和维持：（i）七氟醚（硫喷妥4-5mg / kg和七氟醚2.0-2.5体积％的50％空气）; （ii）总静脉内麻醉（Tiva;丙卵醇 - Remifentanil [靶血液浓度2.5-3.5μg/ ml，分别为3.5-4.5 ng / ml）;或（iii）组合吸入和静脉内麻醉（七氟醚在50％空气中的1.0体积％，分别为50％空气Plus remofentanil [靶血液浓度1.5-2.5μg/ ml和2.5-3.5ng / ml）。术后0-24小时评估PONV的发病率和严重程度和救援止吐学的需求。总体而言，与七氟醚基团相比，TIVA和合并组的PONV的发生率显着降低（分别为33.9％，39.0％和64.4％）。总之，用异丙酚 - 雷芬菊酯或七氟醚-Phofofol-remifentanil的麻醉维持降低了与单独的七氟醚相比PONV的发生率。

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