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首页> 外文期刊>Journal of King Saud University >Green synthesis of silver nanoparticles from Neurada procumbens and its antibacterial activity against multi-drug resistant microbial pathogens
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Green synthesis of silver nanoparticles from Neurada procumbens and its antibacterial activity against multi-drug resistant microbial pathogens

机译：来自 Neurada Procumbens 对多种耐药微生物病原体的抗菌活性

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摘要

The aim of this work was to develop a new biological process for the fabrication of silver nanoparticles (Ag-NPs) using the extract of a xerophytic plant (Neurada procumbens) as a reducing agent. The fabricated Ag-NPs can effectively control multi-drug resistant gram-negative rods (MDR-GNRs), which were isolated from the Buraidah Central Hospital (BCH), Saudi Arabia. The predominant MDR-GNR bacteria includedKlebsiella pneumoniae, Acinetobacter baumannii,andEscherichia coli. The Ag-NPs were examined by diverse spectral and analytical techniques, and then their antibacterial effects against MDR bacteria were determined. The UV spectroscopy showed absorption peaks between 400 and 455?nm specific to AgNPs. The SEM and TEM results showed a smallsize of Ag-NPs in a range of about 20–50?nm. The XRD pattern showed three major distinctive peaks of Ag-NPs at 38.1°, 44.3° and 64.4° confirming the presence of Ag-NPs. Three multidrug-resistant bacterial strains were used to determine antimicrobial activity by the well-diffusion method. The present workillusrates that synthesized Ag-NPs from the aqueous leaf extract ofNeurada procumbensshow considerable antibacterial potential against MDR clinical isolates from different patient samples at BCH.
机译：这项工作的目的是利用磷酸盐植物（Neurada Provumbens）的提取物作为还原剂制造银纳米颗粒（AG-NPS）的新生物学方法。制造的AG-NPS可以有效地控制来自沙特阿拉伯巴德安中央医院（BCH）的多药耐药革兰阴棒（MDR-GNR）。主要的MDR-GNR细菌包括肺炎肺炎，AndeScherichia Coli。通过多样化的光谱和分析技术检查AG-NPS，然后测定它们对MDR细菌的抗菌作用。 UV光谱显示在400-455℃之间的吸收峰，特异于AgNPS。 SEM和TEM结果表明，AG-NPS的小型在约20-50纳米的范围内。 XRD模式显示38.1°，44.3°和64.4°的Ag-NPS的三个主要独特峰，确认存在Ag-NPS。使用三种多药抗性细菌菌株通过良好的扩散方法确定抗微生物活性。本发明的工作组合成Ag-NPS来自含水叶片提取物的ag-NPS，PCCH的不同患者样品的MDR临床分离株的相当大的抗菌潜力。

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