...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of King Saud University >Challenging multidrug-resistant urinary tract bacterial isolates via bio-inspired synthesis of silver nanoparticles using the inflorescence extracts of Tridax procumbens
【24h】

Challenging multidrug-resistant urinary tract bacterial isolates via bio-inspired synthesis of silver nanoparticles using the inflorescence extracts of Tridax procumbens

机译：通过生物启发性的抗性尿路细菌分离素利用 tridax procumbens 斜体合成银纳米粒子的生物纳米粒子合成

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The increasing drug resistance pattern in bacterial pathogens promotes the need to find out alternative strategies to ensure human health. In the imperative lookout for effective drugs to combat multidrug-resistant bacteria, silver nanoparticles (AgNPs) are given priorities. Hence in the present approach, AgNPs were synthesized using the extract of the inflorescence of a medicinal plant, and its antibacterial activity against multidrug-resistant uropathogens was studied. For the synthesis of AgNPs, the inflorescence of a medicinal plantTridax procumbenswas subjected to a microwave irradiation technique. The characteristics of the synthesized nanoparticles (NPs) were analyzed by using UV–visible spectroscopy (UV–Vis), Dynamic light scattering device (DSL), Scanning electron microscope (SEM), Fourier-transform infrared (FTIR) spectroscopy and Zeta potential analyzer. The synthesized AgNPs were with unique optical morphology and semi-spherical shape having irregular contour with the size range 40.0–52.5?nm. The bacterial isolatesEscherichia coli, Klebsiella pneumoniae,Pseudomonas aeruginosa, and Gram-positiveStaphyloccocus saprophyticusfrom urinary tract infected persons that showed resistance to more than ten antibiotics were chosen for AgNPs impact analysis. The mean diameter of zone of inhibition (in mm) for the different isolates at the dose of 50?μg/mL concentration showed a maximum forS. saprophyticus(21.0?±?1.7?mm)followed byP. aeruginosa(18.0?±?1.3?mm),K. pneumoniae(18.0?±?0.09?mm) andE. coli(17.0?±?1.70). The MIC values for the isolates showed a minimum forS. saprophyticus(2.5?μg/mL) and a maximum forE. coli(55.5?μg/mL). The results show that theT. procumbensphytochemicals inspired silver nanoparticles can be explored further to develop useful antibiotics.
机译：细菌病原体中耐药模式的增加促进了发现替代策略以确保人类健康。在对抗多药物的有效药物的迫切期望中，给予银纳米颗粒（AgNP）优先事项。因此，在本方法中，使用药用植物的开采的提取物合成AgNP，研究了对多药耐药肝炎的抗菌活性。对于AgNP的合成，药用植物血管曲线衰竭的花序经受微波辐射技术。通过使用UV可见光谱（UV-VI），动态光散射装置（DSL），扫描电子显微镜（SEM），傅里叶变换红外（FTIR）光谱和Zeta电位分析仪来分析合成纳米颗粒（NPS）的特性。合成的agnps具有独特的光学形态和半球形，具有不规则的轮廓，尺寸范围为40.0-52.5μm。细菌分离株Coli，Klebsiella Pneumoniae，假单胞菌铜绿假单胞菌和革氏症状感染患者的尿道感染者，用于抗agnps的影响分析。在50Ωμg/ mL浓度的剂量下为不同分离物的抑制区（mM）的平均直径显示出最大的含量。 saprophyticus（21.0？±1.7？mm），然后是BYP。铜绿假单胞菌（18.0？±1.3？mm），k。肺炎（18.0？±0.09？mm）ande。 Coli（17.0？±？1.70）。隔离物的麦克风值显示为最小。 saprophyticus（2.5？μg/ ml）和最大前。大肠杆菌（55.5？μg/ ml）。结果表明他们的特点。可以进一步探索倾向于培养银纳米粒子以进行有用的抗生素。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号