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首页> 外文期刊>Journal of Natural Science Biology and Medicine >A comparative study of three scoring systems on palpable breast aspirates at a tertiary health-care center: A cross-sectional study
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A comparative study of three scoring systems on palpable breast aspirates at a tertiary health-care center: A cross-sectional study

机译:三级保健中心可触及乳房吸气中三种评分系统的比较研究:横截面研究

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Background: The cytological grading system in fine-needle aspiration of breast lumps helps the surgeons to decide the method of management and assess the survival rate. However, till date, no single cytological grading system for breast aspirates has been adapted in routine practice. Hence, a comparative study of three different grading systems was done. Materials and Methods: This is a retrospective study conducted from January 2016 to June 2018. The stained aspirated smears of breast lump were assessed for cytomorphologic features and graded as per the Modified Masood's Scoring Index (MMSI), National Cancer Institute (NCI) Cytological Grading System, and Robinson's cytological grading and compared with histological diagnosis (four categories) and modified Scarff–Bloom–Richardson's scoring system (carcinoma cases). Results: The MMSI system had a sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and diagnostic accuracy of 80%, 100%, 100%, 92.86%, and 94.44%, respectively. The NCI system had a sensitivity, specificity, PPV, NPV, and diagnostic accuracy of 60%, 97.44%, 90.0%, 86.36%, and 87.04%, respectively. The Robinson's cytological grading system had a sensitivity, specificity, PPV, NPV, and diagnostic accuracy of 100%, 84.62%, 71.43%, 100%, and 88.89%, respectively. Conclusion: Robinson's scoring system is the system with maximum sensitivity and is most effective in subcategorizing only malignant breast lesions. MMSI is the system with maximum specificity, PPV, and diagnostic accuracy, and can be considered as the standard grading system for both benign and malignant breast lesions on cytology.
机译:背景:乳房肿块的细针吸入中的细胞学分级系统有助于外科医生决定管理方法并评估存活率。然而,直到迄今为止,没有单一细胞学分级系统用于常规实践。因此,完成了三种不同分级系统的比较研究。材料和方法:这是从2016年1月到2018年6月进行的回顾性研究。评估乳腺肿块的染色吸气涂片对于细胞形态特征,并根据改性的Masood的评分指数(MMSI),国家癌症研究所(NCI)细胞学分级进行评分系统和罗宾逊的细胞学分级,与组织学诊断(四类)和改装的Scarff-Bloom-Richardson评分系统(癌病例)进行比较。结果:MMSI系统具有敏感性,特异性,阳性预测值(PPV),阴性预测值(NPV),诊断准确度分别为80%,100%,100%,92.86%和94.44%。 NCI系统的敏感性,特异性,PPV,NPV,诊断准确性分别为60%,97.44%,90.0%,86.36%和87.04%。罗宾逊的细胞学分级系统分别具有敏感性,特异性,PPV,NPV和诊断准确度,分别为100%,84.62%,71.43%,100%和88.89%。结论:罗宾逊的得分系统是具有最大敏感性的系统,并且在副类别中只有最有效的恶性乳房病变。 MMSI是具有最大特异性,PPV和诊断准确性的系统,并且可以被视为细胞学上良性和恶性乳房病变的标准分级系统。

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