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首页> 外文期刊>Journal of Nepal Paediatric Society >Differentiating Scrub Typhus, Dengue Fever and Typhoid Fever in Indian Children Presenting with Acute Febrile Illness
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Differentiating Scrub Typhus, Dengue Fever and Typhoid Fever in Indian Children Presenting with Acute Febrile Illness

机译：在印度儿童患有急性发热疾病的印度儿童中差异

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Introduction: The disease spectrum of dengue, scrub typhus and typhoid presenting as acute febrile illness is often a diagnostic dilemma to the clinician. The purpose of this study is to compare the clinical features and laboratory parameters of children suffering from typhoid, dengue and scrub typhus and use these parameters in early identification of scrub typhus before conclusion is made from serological diagnosis.Methods: A retrospective observational analytical study was conducted among children presenting with acute febrile illness in a tertiary care level hospital. Over the period of one year 113 cases were identified of which 39 were dengue, 44 were typhoid and 30 were scrub typhus.Results: The mean age of the children was 7.45 ± 2.98 years, median was eight with an interquartile range of six to ten years. The male to female ratio was 1.3:1. Symptoms of vomiting (61.54%), headache (46.15%) and hepatomegaly (47.37%) were significantly higher among children with dengue fever. A significantly higher number of children with scrub typhus fever had temperature above 40°C. The incidence of low haemoglobin, raised C reactive protein, raised ALT and low albumin levels were significantly higher in them. Children with acute febrile illness having temperature 40°C, absolute neutrophil/lymphocyte ratio 2 early in the illness were more likely to suffer from scrub typhus with relative probability ratio (RPR) of 25.68 and 10.57 respectively (p 0.001). Children with WBC 5000/mm3 were more likely to be suffering from dengue with RPR of 10.60 (p 0.001).Conclusion: Children with acute febrile illness with temperature 40°C and absolute neutrophil/lymphocyte ratio 2 early in the illness were more likely to be suffering from scrub typhus.
机译：简介：登革热的疾病，磨砂动脉和伤寒呈现为急性发热疾病，往往是临床医生的诊断困境。本研究的目的是比较患有伤寒，登革热和磨砂动脉斑疹的儿童的临床特征和实验室参数，并在结论是由血清学诊断进行之前的早期鉴定中使用这些参数。方法：一种回顾性观察分析研究在第三级护理水平医院中患有急性发热疾病的儿童进行。在一年的时间内，鉴定了39例，其中39例是登革热，44例是伤寒，30人磨砂伤寒。结果：儿童的平均年龄为7.45±2.98岁，中位数是八分之一的六到十个年。男性与女性比例为1.3：1。登革热的儿童，呕吐的症状（61.54％），头痛（46.15％）和肝肿大（47.37％）显着高出显着高。具有磨砂动卵热的患儿的显着较多的儿童具有高于40℃的温度。低血红蛋白，升高的C反应蛋白，升高的Alt和低白蛋白水平的发病率显着高。患有温度的急性发热疾病的儿童> 40℃，绝对中性粒细胞/淋巴细胞比例> 2患者的2次疾病早期患有25.68和10.57的相对概率比（RPR）的磨损伤寒伤寒毛虫（P <0.001）。 WBC <5000 / mm3的儿童更有可能患有10.60的RPR（P <0.001）。结论：急性发热性疾病的儿童，温度> 40°C和绝对中性粒细胞/淋巴细胞比例>疾病早期2更有可能遭受磨碎的伤寒伤寒。

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