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首页> 外文期刊>Journal of Ophthalmology >Management of Corneal Ectasia after LASIK with Phototherapeutic Keratectomy Combined with Photorefractive Keratectomy and Collagen Cross-Linking
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Management of Corneal Ectasia after LASIK with Phototherapeutic Keratectomy Combined with Photorefractive Keratectomy and Collagen Cross-Linking

机译：光疗角膜切除术结合光焦畸形和胶原交联术后角膜外亚肌肌瘤的管理

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Background. To evaluate the efficacy of phototherapeutic keratectomy (PTK) combined with photorefractive keratectomy (PRK) and riboflavin with ultraviolet-A collagen cross-linking (CXL), performed sequentially on the same day, in the management of corneal ectasia after LASIK. Methods. This retrospective review comprised consecutive patients with corneal ectasia after LASIK. The patients were administered PTK and PRK on the previous corneal flap, and CXL was given on the same day by the same surgeon. The main outcome measures included age, sex, uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), spherical equivalent refraction, cylinder equivalent refraction, steep and flat keratometries (K), central corneal thickness (CCT), endothelial cell count, corneal haze, and ectasia stability. Mean follow-up period was 6, 12, and 24 months. Results. Sixteen eyes of twelve patients were included in the study. Twenty-four months after administration of PTK combined with PRK and CXL, a significant improvement in UDVA was observed. Mean cylinder equivalent refraction was significantly reduced at 6, 12, and 24 months postoperatively. However, no significant reduction was observed in spherical equivalent refraction. A significant reduction in the flat K and steep K values was observed. No significant change in mean CCT value was observed. Mean endothelial cell count and morphology were unchanged between preoperative and postoperative patients. In addition, no obvious corneal haze was observed. Conclusions. PTK combined with PRK and CXL on the same day is a safe and effective treatment in improving visual acuity in selected patients with corneal ectasia after LASIK.
机译：背景。为了评估光照角膜切除术（PTK）与紫外线 - 一种胶原蛋白交联（CXL）结合的光治疗性角膜切除术（PTK）与紫外线交联（CXL）的效果，在同一天进行，在LASIK之后的角膜外肌的管理中依次进行。方法。此回顾性审查包括LASIK后连续患有角膜外胚层的患者。将患者施用PTK和PRK在前一个角膜皮瓣上，CXL在同一天给出了同一外科医生。主要结果措施包括年龄，性别，未矫正距离视力（UDVA），矫正距离视力（CDVA），球形等效折射，气缸等效折射，陡峭和平坦的角膜塔（K），中央角膜厚度（CCT），内皮细胞计数，角膜雾霾和异端稳定性。平均随访时间为6,12和24个月。结果。这项研究中包含十六只患者的十四只患者。施用PTK与PRK和CXL合并后二十四个月，观察到UDVA的显着改善。平均气缸当量折射在术后6,12和24个月显着降低。然而，在球面等效折射中没有观察到显着的减少。观察到扁平K和陡峭k值的显着降低。观察到平均CCT值没有显着变化。术前和术后患者之间的平均内皮细胞计数和形态学不变。此外，没有观察到明显的角膜雾霾。结论。 PTK在同一天与PRK和CXL联合是一种安全有效的治疗，在LASIK之后改善了角膜外肌的选定患者的视力。

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