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首页> 外文期刊>Journal of Nutritional Science and Vitaminology >Dose Effect of Bovine Lactoferrin Fortification on Iron Metabolism of Anemic Infants
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Dose Effect of Bovine Lactoferrin Fortification on Iron Metabolism of Anemic Infants

机译：牛乳铁蛋白的剂量效应对贫血婴儿铁代谢的影响

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To evaluate the effect of iron-fortified formula with different concentrations of bovine lactoferrin (bLF) on improvement of anemic status in term infants who were previously breast-fed. A randomized, controlled, open, and post-market intervention study. A total of 108 infants aged 6-9 mo who were previously breast-fed and weaned were selected. The subjects were divided into three groups with the sequence of outpatient: fortified group 1 (FG1) with a bLF concentration of 38 mg/100 g, FG2 with 76 mg/100 g bLF, FG0 with no bLF. The intervention duration was 3 mo. Weight, height, head circumference and the concentration of hemoglobin (Hb), serum ferritin (SF), serum transferring receptor (sTfR) were measured and sTfR-SF index (TFR-F index) and total body iron content (TBIC) were computed before and after intervention. The primary outcome measures were obtained from 96 infants (35, 33 and 28 for FG0, FG1 and FG2, respectively). After 1 mo of intervention, the changes of Hb level showed no significant difference ( p 0.05) among the three groups, however, the Hb level of infants in FG2 were significantly higher than those of infants in the other two groups after 3 mo of intervention ( p 0.05). The present data indicated that the formula fortified with 76 mg/100 g bLF positively affected the Hb of anemic infants who were previously breastfed when compared with fortification with 38 mg/100 g bLF and no bLF fortification.
机译：以不同浓度的牛乳铁蛋白（BLF）评价铁强化配方的作用提高患者患者患者的贫血地位。随机，受控，开放和后期市场干预研究。选择了6-9岁以前的108名婴儿喂养和断奶的婴儿。将受试者分为三组，具有门诊序列：强化基团（FG1），BLF浓度为38mg / 100g，FG2，具有76mg / 100g BLF，FG0，没有BLF。干预持续时间为3 mo。测量测量血红蛋白（Hb），血清转移受体（STFR）的重量，高度，头圆周和血红蛋白（SF），血清转移受体（STFR）和STFR-SF指数（TFR-F指数）和总体铁含量（TBIC）在干预之前和之后。主要结果措施分别从96名婴儿（35,33和28例，分别为FG0，FG1和FG2）。在干预1次后，三组的Hb水平的变化显示出没有显着差异（p> 0.05），然而，FG2中婴儿的HB水平明显高于3℃后其他两组中的婴儿干预（P <0.05）。目前的数据表明，用76mg / 100g BLF强化的配方伴随着先前母乳喂养的血液婴儿的HB，与38mg / 100g BLF和没有BLF防御性的强化。

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