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首页> 外文期刊>Journal of primary care & community health. >Assessment of Antibiotic Prescribing Patterns at Outpatient Pharmacy Using World Health Organization Prescribing Indicators
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Assessment of Antibiotic Prescribing Patterns at Outpatient Pharmacy Using World Health Organization Prescribing Indicators

机译：利用世界卫生组织规定指标评估门诊药房的抗生素规定模式

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Background: Overuse of antibiotics is a common problem in health care, which leads to unnecessary expenditure on drugs, raised risk of adverse reactions, and the development of antimicrobial resistance. Inappropriate prescribing habits lead to ineffective and unsafe treatment, worsening of disease and increment of health care costs. The aim of this study was to assess antibiotic prescribing patterns using World Health Organization prescribing indicators at the outpatient Pharmacy Department of University of Gondar referral hospital, Gondar, Northwest Ethiopia. Methods: A retrospective cross-sectional study was conducted. One-year prescription data was collected from prescription and prescription registration books retained at the pharmacy store. World Health Organization/International Network of Rational Use of Drugs prescribing indicators were utilized to measure rational use of drugs with due focus on antibiotics prescribing patterns. The collected data was analyzed using SPSS version 20. Results and Discussion: A total of 968 drugs were prescribed from 600 patient encounters. The average number of drugs per encounter was 1.6. The percentage of encounters in which an antibiotics and injections were prescribed was 69.7% and 6.3% respectively. Amoxicillin (28.5%) followed by ciprofloxacin (12%) and metronidazole(11.1%) were the most commonly prescribed antibiotics. The percentage of drugs prescribed from essential drugs list and by generic name was 95.3% and 96%, respectively. Rate of antibiotics prescribing showed deviation from the standard recommended by World Health Organization whereas polypharmacy, injectable prescribing pattern, uses of brand names, and prescription of drugs from the National Essential Drugs List were not found to be a significant problem though there were slight deviations from the standard. Conclussion: Interventions aimed at improving the antibiotic prescribing patterns need to be implemented so as to prevent the inappropriate use of antibiotics and avoid further complications.
机译：背景：过度使用抗生素是医疗保健中的常见问题，这导致了不必要的药物支出，提高了不良反应的风险，以及抗微生物抗性的发展。不适当的处方习惯导致无效和不安全的治疗，疾病恶化和养护费的增量。本研究的目的是利用世界卫生组织在戈达尔戈尼岛大学门诊药剂部门，戈尼尔，西北埃塞俄比亚的门诊药剂部门评估抗生素规定模式。方法：进行回顾性横截面研究。从药房店保留的处方和处方注册书收集一年的处方数据。世界卫生组织/国际合理使用药物的资金按定规定指标用于衡量可合理使用药物，以适当关注抗生素的处方模式。使用SPSS版本20分析收集的数据。结果和讨论：共有968名药物遭受600名患者遭遇。每次遭遇的药物的平均数量为1.6。抗生素和注射的遭遇的百分比分别为69.7％和6.3％。阿莫西林（28.5％），其次是环丙沙星（12％）和甲硝唑（11.1％）是最常见的抗生素。从基本药物清单和通用名称规定的药物的百分比分别为95.3％和96％。抗生素规定的率显示出世界卫生组织推荐的标准的偏差，而多药物，可注射的规定模式，品牌名称的使用以及来自国家必要药物列表的药物的处方并未发现是一个重要的问题，但虽然有轻微的偏差标准。结论：需要实施旨在改善抗生素处方模式的干预，以防止抗生素使用不当，避免进一步的并发症。

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