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首页> 外文期刊>Journal of Sports Medicine >Diagnosis of Overtraining Syndrome: Results of the Endocrine and Metabolic Responses on Overtraining Syndrome Study: EROS-DIAGNOSIS
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Diagnosis of Overtraining Syndrome: Results of the Endocrine and Metabolic Responses on Overtraining Syndrome Study: EROS-DIAGNOSIS

机译：过度训练综合征的诊断：内分泌和代谢反应对过度训练综合征研究的结果：EROS诊断

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Objectives. Overtraining syndrome (OTS), a common dysfunction among elite athletes, causes decreased performance and fatigue and has no standardized diagnostic criteria. The Endocrine and Metabolic Responses on Overtraining Syndrome (EROS) study identified more than 45 potential biomarkers of OTS. In the present study, we hypothesized that combinations of these biomarkers could be an accurate diagnostic tool for OTS. Methods. We selected parameters with largest difference and fewest overlapping results compared to healthy athletes and highest feasibility and reproducibility. Among the multiple combinations attempted, we chose those that did not show overlapping results, according to the objective. Results. We included 11 clinical parameters, 4 basal hormones, and 5 hormonal responses in Insulin Tolerance Test (ITT). The three selected diagnostic tools were the (i) EROS-CLINICAL, with only clinical parameters, which was suitable as an initial assessment for athletes suspected of OTS; (ii) EROS-SIMPLIFIED, with clinical parameters and basal hormones, when the EROS-CLINICAL was inconclusive; and (iii) EROS-COMPLETE, with basal and hormonal responses to stimulation tests, which was valuable for population-based screening, research purposes, and unusual presentations of OTS. Conclusion. We identified innovative tools with 100% accuracy for the diagnosis of OTS, without the need to exclude confounding disorders.
机译：目标。过度训练综合征（OTS），精英运动员中的常见功能障碍，导致性能和疲劳降低，没有标准化的诊断标准。对过度训练综合征（EROS）研究的内分泌和代谢反应鉴定了超过45个潜在的OTS生物标志物。在本研究中，我们假设这些生物标志物的组合可能是对OTS的准确诊断工具。方法。与健康运动员相比，我们选择了最大差异和最少的重叠结果的参数，以及最高的可行性和再现性。根据目的，我们选择了那些没有表现出重叠结果的组合。结果。我们包括11种临床参数，4个基础激素和胰岛素耐受试验中的5个激素反应（ITT）。三种选定的诊断工具是（i）EROS临床，只有临床参数，适合作为疑似疑似OTS的运动员的初步评估; （ii）当临床临床缺失时，临床参数和基底激素的EROS简化; （iii）eros-complete，对刺激测试的基础和荷尔蒙反应，对于基于人口的筛查，研究目的和对OTS不寻常的介绍来说是有价值的。结论。我们确定了100％准确的创新工具，用于诊断OTS，无需排除混淆障碍。

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