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首页> 外文期刊>Journal of the International Society of Sports Nutrition >β-Alanine supplementation increased physical performance and improved executive function following endurance exercise in middle aged individuals
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β-Alanine supplementation increased physical performance and improved executive function following endurance exercise in middle aged individuals

机译：β-丙氨酸补充剂在中年个人耐力运动后增加了物理性能和改进的执行功能

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Sarcopenia, a reduction in muscle mass and function seen in aging populations, may be countered by improving systemic carnosine stores via beta-Alanine (β-alanine) supplementation. Increasing systemic carnosine levels may result in enhanced anti-oxidant, neuro-protective and pH buffering capabilities. This enhancement should result in improved exercise capacity and executive function. Twelve healthy adults (average age?=?60.5?±?8.6?yrs, weight?=?81.5?±?12.6?kg) were randomized and given either 2.4?g/d of β-alanine (BA) or Placebo (PL) for 28?days. Exercise capacity was tested via bouts on a cycle ergometer at 70% VO2 peak. Executive function was measured by Stroop Tests 5?min before exercise (T1), immediately before exercise (T2), immediately following fatigue (T3), and 5?min after fatigue (T4). Lactate measures were taken pre/post exercise. Heart rate, Rating of Perceived Exertion (RPE) and VO2 were recorded throughout exercise testing. PRE average time-to-exhaustion (TTE) for the PL and BA group were not significantly different (Mean?±?SD; 9.4?±?1.4mins vs 11.1?±?2.4mins, respectively, P?=?0.7). POST BA supplemented subjects cycled significantly longer than PRE (14.6?±?3.8mins vs 11.1?±?2.4mins, respectively, P?=?0.04) while those given PL did not (8.7?±?2.4mins vs 9.4?±?1.4mins, respectively, P?=?0.7). PL subjects were slower in completing the Stroop test POST at T4 compared to T3 (T3?=?-?13.3?±?8.6% vs T4?=?2.1?±?8.3%, P?=?0.04), while the BA group (T3?=?-?9.2?±?6.4% vs T4?=?-?2.5?±?3.5%, P?=?0.5) was not. POST lactate production expressed a trend when comparing treatments, as the BA group produced 2.4?±?2.6?mmol/L more lactate than the PL group (P?=?0.06). Within group lactate production for BA (P?=?0.4) and PL (P?=?0.5), RPE (P?=?0.9) and heart rate (P?=?0.7) did not differ with supplementation. BA supplementation increased exercise capacity and eliminated endurance exercise induced declines in executive function seen after recovery. Increased POST TTE coupled with similar PRE vs POST lactate production indicates an improvement in the ability of BA to extend exercise durations. Furthermore, by countering endurance exercise's accompanying deficits in executive function, the aging population can maintain benefits from exercise with improved safety.
机译：SARCOPENIA，肌肉质量的降低和在老龄化群体中的功能，可以通过β-丙氨酸（β-丙氨酸）补充剂改善全身肉核苷酸储存来对抗。增加全身肉核苷酸水平可能导致增强的抗氧化剂，神经保护剂和pH缓冲能力。这种增强应导致锻炼能力和执行功能提高。十二个健康的成年人（平均年龄？= 60.5？±±8.6？YRS，重量？=Δ= 81.5？±12.6μl）被随机化，给予2.4〜丙氨酸（BA）或安慰剂（PL ）28个？天。在70％VO2峰值的循环测力计上通过BOUT测试运动能力。执行功能通过Tromp试验测量5≤min（t1），在运动前（t2），紧接在疲劳（t3）后立即进行疲劳（t3），疲劳后5？min（t4）。乳酸疗法措施进行预/术后。在整个运动测试中记录了心率，感知劳动（RPE）和VO2的额定值。 PL和BA组的预平均耗尽（TTE）没有显着差异（平均值？±αSD; 9.4？±1.4mins vs 11.1？±2. 4.4mins，p？= 0.7）。 POST BA补充受试者循环显着长于前（14.6？±3.8分钟，分别为11.8m，分别，P？= 0.04），而那些给定的PL没有（8.7？±2. 4.4min vs 9.4？±？ 1.4mins分别，p？= 0.7）。与T3相比，Pl受试者在T4完成T4的速率测试柱（T3？= 13.3？±8.6％Vs T4？=？2.1？±8.3％，P？= 0.04），而BA组（T3？=？ - ？9.2？±6.4％Vs t4？=？ - ？2.5？±3.5％，p？= 0.5）不是。乳酸后产生的趋势表达了比较治疗时的趋势，因为BA组产生2.4？±2.6？2.6？mmol / l比PL组更乳酸（p？= 0.06）。在组内乳酸盐产生（p？= 0.4）和PL（p？= 0.5），RPE（p？= 0.9）和心率（p？= 0.7）与补充没有不同。 BA补充更高的运动能力和消除恢复后执行职能的耐久性锻炼诱导的下降。增加的PETTTTE与类似的前乳酸乳酸乳酸乳酸产量增加表明BA延长运动持续时间的能力提高。此外，通过对执行功能的持续赤字进行反击持续的缺陷，衰老人口可以通过改善安全性维持锻炼的益处。

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