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首页> 外文期刊>Journal of Young Pharmacists >Role of Pharmacist Intervention in the Management of Anemia Associated with Chronic Kidney Diseases at the Hemodialysis Setting
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Role of Pharmacist Intervention in the Management of Anemia Associated with Chronic Kidney Diseases at the Hemodialysis Setting

机译：药剂师干预在血液透析环境中与慢性肾疾病相关的贫血症的作用

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Background: The potential impact of pharmacist interventions could improve health outcomes of patients with anemia. However, this attempt has not been documented yet in the developing countries. Aim of the study is to investigate the effect of pharmacist interventions in optimizing management of anemia associated with chronic kidney disease. Methods: An interventional randomized control trial was carried out on 120 anemic patients on hemodialysis for eight months. The impact of the pharmacist’s interventions in optimizing anemia management to reach hemoglobin target were investigated. Data were analyzed by GraphPad Prism version 8.2.1. Results: During 16-week period, 1646 interventions and recommendations were performed. The interventions were at the physician, patients, drugs, hospital and administrative level. At the physician level a total of 180 (10.9%) recommendations were proposed, at the drug level, the pharmacist provided 595 (36.1%) interventions which were mainly related to erythropoietin and iron dose adjustment. At the patient and the hospital level 734 (44.6%) and 137 (8.3%) interventions have been made respectively. Hemoglobin level increased significantly to (11.25 ± 2.29) after 16-weeks in interventional group ( p -value 0.5), while in non-interventional group it was increased to (9.99 ± 2.54) at 16th week although the change was significant compare to the baseline level but it has not reached the target hemoglobin level. In the interventional group 39 (65%) patients reached the target hemoglobin while it was 25 (41.6%) in non-interventional group with a significant difference between both groups ( p -value =0.017). Conclusion: In conclusion the implementation of pharmacist intervention in patients with chronic kidney disease-associated anemia improved hemoglobin level and healthcare outcomes.
机译：背景：药剂师干预的潜在影响可以改善贫血患者的健康状况。但是，此次尝试尚未在发展中国家记录。该研究的目的是探讨药剂师干预在优化与慢性肾病相关的贫血管理中的影响。方法：在血液透析患者中​​进行介入随机对照试验八个月。调查了药剂师干预优化贫血管理治疗血红蛋白目标的影响。通过GraphPad Prism版本8.2.1分析数据。结果：在16周期间，进行1646项干预措施和建议。干预措施是医生，患者，毒品，医院和行政层面。在医生级别，共有180名（10.9％）建议，在药房，药剂师提供595（36.1％）的干预措施，主要与促红细胞生成素和铁剂量调节有关。在患者和医院734级（44.6％）和137（8.3％）干预措施。介入组16周后血红蛋白水平显着增加到（11.25±2.29）（P-value <0.5），而在非介入群体中，第16周增加到（9.99±2.54），尽管变化是显着的比较基线水平但它尚未达到目标血红蛋白水平。在介入第39族（65％）患者中达到靶血红蛋白，而在非介入基团中为25（41.6％），两组之间具有显着差异（P-Value = 0.017）。结论：总之，慢性肾病相关性贫血患者的药剂师干预改善血红蛋白水平和医疗成果。

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