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Prevalence and Incidence of Syphilis among Volunteer Blood Donors in Israel

机译:以色列志愿者献血者中梅毒的患病率和发病率

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Data of 1,290,222 volunteer blood donors, in a 5-year period, was analyzed for prevalence and incidence of syphilis. Subsequent testing of donations positive in Treponema pallidum hemagglutination assay included Venereal Disease Research Laboratory and fluorescent Treponemal antibody absorption. Stepwise logistic regression model was used to identify positive syphilis serology. Prevalence of syphilis was 47  100,000, similar in men and women and increased significantly with age (). Native Israelis had the lowest prevalence rate of syphilis (21  100,000), while a significantly higher prevalence was found among immigrants from Africa, Eastern Europe, and South America (odds ratios of 19.0, 10.8, and 7.3, resp., for each). About 33.2% of the seropositive donors had evidence of recent infection, and 66.8% had past infections. Incidence rate reached 8  100,000 person-years. Coinfection with HIV, HCV, and HBV was calculated as 8%, 1.88%, and 0.37% for positive donations, respectively. The data support the need to continue screening blood donors in Israel for syphilis and employ preventive measures to populations at risk, in order to improve public health, blood safety, and quality. A subsequent study to assess blood donors’ knowledge, attitude, and behavior is planned. In times of global migration this information may be useful to blood services worldwide.
机译:1,290,222个志愿者献血者的数据,在5年期间,分析了梅毒的患病率和发病率。随后在蛋白质血液血凝术中施用阳性的施加阳性,包括性病研究实验室和荧光纤维抗体抗体吸收。逐步逻辑回归模型用于识别正梅毒血清学。梅毒的患病率为47 100,000,男性和女性相似,随着年龄()的显着增加。原生以色列人的梅毒普及率最低(21 100,000),而非洲,东欧和南美洲的移民在普及中发现了显着更高的流行(19.0,19.0,10.8和7.3,每次)。约33.2%的血清阳性捐赠者有近期感染的证据,66.8%过去感染。发病率达到8万人 - 年8万人。用艾滋病毒,HCV和HBV繁殖,分别计算为阳性捐赠的8%,1.88%和0.37%。数据支持需要在以色列中继续筛查梅毒的献血者,并雇用风险的人口预防措施,以改善公共卫生,血液安全和质量。计划评估献血者知识,态度和行为的后续研究。在全球迁移的时期,此信息可能对全球血液服务有用。

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