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Using Basic Ethical Principles to Evaluate Safety Efforts in Transfusion Medicine

机译:利用基本道德原则评估输血医学中的安全努力

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Pursuit of pharmaceutical purity of the blood in the bag has led to a shrinking donor base and a significantly more expensive product. Decisions regarding new infectious marker testing and donor deferrals have typically been made emphasizing decreasing one specific risk without considering the effect the intervention will have on the overall safety and availability of blood transfusion. Regulations have been formulated by governmental agencies with limited input from the medical community. The decision making process has lacked risk benefit analyses and has not had the robustness associated with spirited discussions. Policies made in this manner may result in certain risks being decreased but can also have adverse unintended consequences. Being guided by the ethical principles of nonmaleficence, beneficence, autonomy, and justice, we need to evaluate our actions in the context of overall blood safety rather than narrowly focusing on any one area.
机译:追求袋中的血液的药物纯度导致了缩小的供体基础和更昂贵的产品。关于新的传染性标记测试和捐赠者推迟的决定通常是强调降低一种特定风险,而不考虑干预对整体安全性和输血的可用性的影响。政府机构由医学界投入有限的政府机构制定。决策过程缺乏风险益处分析,并没有与激烈的讨论相关的稳健性。以这种方式制造的政策可能导致某些风险减少,但也可能具有不良后果不利。被非公私,益(自主,自主权和正义的道德原则为指导,我们需要在整体血液安全的背景下评估我们的行为,而不是勉强关注任何一个领域。

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