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首页> 外文期刊>Journal of Thoracic Disease >Changing etiological frequency of chronic cough in a tertiary hospital in Shanghai, China
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Changing etiological frequency of chronic cough in a tertiary hospital in Shanghai, China

机译：中国上海大专慢性咳嗽的病因频率改变慢性咳嗽

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Background: The frequency distributions of the etiologies of chronic cough have changed over time. This study aimed to investigate the changing etiological frequency of chronic cough in a tertiary hospital in Shanghai, China, and to explore the clinical significance. Methods: Medical records of 1,311 patients with chronic cough who visit our hospital between January 2009 and December 2016 were retrospectively reviewed. The etiologies of chronic cough were identified according to a standardized step-by-step diagnostic protocol and the changes in the etiological frequency of chronic cough over the years were using the Chi-squared (? 2 ) test. Results: Cough variant asthma (CVA) (449/1,311, 34.2%), gastroesophageal reflux-related chronic cough (GERC) (374/1,311, 28.5%), upper airway cough syndrome/postnasal drip syndrome (UACS/PNDs) (241/1,311, 18.4%), atopic cough (AC) (188/1,311, 14.3%), and non-asthmatic eosinophilic bronchitis (NAEB) (147/1,311, 11.2%) were the common causes of chronic cough in descending order. The post-infectious cough (PIC) (39/1,311, 3.0%) and angiotensin-converting enzyme inhibitor (ACEI)-induced cough (25/1,311, 1.9%) were less common. During the 8-year period, the proportion of CVA (? 2 =72.86, P 2 =68.80, P 2 =51.38, P 2 =55.95, P 2 =39.09, P Conclusions: The etiological frequency of chronic cough varies over time, and it may encourage the adjustment of the current diagnostic and therapeutic strategies for chronic cough.
机译：背景：慢性咳嗽病因的频率分布随时间变化。本研究旨在探讨中国上海市三级医院慢性咳嗽的病因频率，探讨临床意义。方法：在2009年1月至2016年1月至2016年12月在2016年12月至2016年12月期间，慢性咳嗽1,311名慢性咳嗽患者的病程。根据标准化的逐步诊断方案确定慢性咳嗽的病因，多年来慢性咳嗽的病因频率的变化使用Chi平方（α2）测试。结果：咳嗽变体哮喘（CVA）（449 / 1,311,34.2％），胃食管反流相关的慢性咳嗽（GERC）（374 / 1,311,28.5％），上气道咳嗽综合征/后滴水综合征（UACS / PNDS）（241 / 1,311,18.4％），特应咳嗽（AC）（AC）（188 / 1,311,14.3％）和非哮喘嗜酸性嗜酸性支气管炎（NAEB）（147 / 1,311,11.2％）是降序慢性咳嗽的常见原因。发后咳嗽（PIC）（39 / 1,311,3.0％）和血管紧张素转换酶抑制剂（ACEI）诱导咳嗽（25 / 1,311,1.9％）不太常见。在8年期间，CVA的比例（α2= 72.86，p 2 = 68.80，p 2 = 51.38，p 2 = 55.95，p 2 = 39.09，P结果：慢性咳嗽的病因频率随着时间的推移而变化，它可能会鼓励调整目前对慢性咳嗽的诊断和治疗策略。

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