...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Medical Microbiology: An Official Journal of the Pathological Society of Great Britain and Ireland >Microbial aetiology of acute diarrhoea in children under five years of age in Khartoum, Sudan
【24h】

Microbial aetiology of acute diarrhoea in children under five years of age in Khartoum, Sudan

机译：苏丹喀土穆五岁以下儿童急性腹泻的微生物病毒

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Diarrhoea is one of leading causes of morbidity and mortality worldwide. Recent estimations suggested the number of deaths is close to 2.5 million. This study examined the causative agents of diarrhoea in children under 5 years of age in suburban areas of Khartoum, Sudan. A total of 437 stool samples obtained from children with diarrhoea were examined by culture and PCR for bacteria, by microscopy and PCR for parasites and by immunoassay for detection of rotavirus A. Of the 437 samples analysed, 211 (48?%) tested positive for diarrhoeagenic Escherichia coli , 96 (22?%) for rotavirus A, 36 (8?%) for Shigella spp., 17 (4?%) for Salmonella spp., 8 (2?%) for Campylobacter spp., 47 (11?%) for Giardia intestinalis and 22 (5?%) for Entamoeba histolytica . All isolates of E. coli (211, 100?%) and Salmonella (17, 100?%), and 30 (83?%) isolates of Shigella were sensitive to chloramphenicol; 17 (100?%) isolates of Salmonella , 200 (94?%) isolates of E. coli and (78?%) 28 isolates of Shigella spp. were sensitive to gentamicin. In contrast, resistance to ampicillin was demonstrated in 100 (47?%) isolates of E. coli and 16 (44?%) isolates of Shigella spp. In conclusion, E. coli proved to be the main cause of diarrhoea in young children in this study, followed by rotavirus A and protozoa. Determination of diarrhoea aetiology and antibiotic susceptibility patterns of diarrhoeal pathogens and improved hygiene are important for clinical management and controlled strategic planning to reduce the burden of infection.
机译：腹泻是全世界发病率和死亡率的主要原因之一。最近的估计表明死亡人数接近250万。本研究检测了苏丹喀土穆郊区5岁以下儿童腹泻的损伤剂。通过培养和PCR用于细菌的培养和PCR，通过微观和PCR进行寄生虫和通过免疫测定来检测来自腹泻的437个粪便样本，用于检测RotaVirus A.在分析的437个样品中，211（48〜％）测试阳性腹泻的腹泻，96（22μm），96（22〜％）用于Shigella SPP的SAVAVIRUS A，36（8-倍）。，Salmonella SPP的17（4倍），弯曲杆菌SPP的8（2？％）。，47（11术治疗组织术语的Giardia Intestinalis和22（5？％）。所有分离物的大肠杆菌（211,100？％）和沙门氏菌（17,100？％）和30（83μl）分离物对氯霉素敏感; 17（100？％）沙门氏菌的分离物，200（94〜％）大肠杆菌的分离物和（78〜Δ％）28分离株的Shigella SPP。对庆大霉素敏感。相反，在大肠杆菌的100（47μl）和16（44℃）分离物的100（47μl）分离物中证实了对氨苄青霉素的抗性。总之，大肠杆菌被证明是本研究中幼儿腹泻的主要原因，其次是轮状病毒A和原生动物。测定腹泻病病原体的腹泻和抗生素敏感性曲线和改善的卫生对临床管理和控制战略计划来说是重要的，以减少感染负担。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号