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首页> 外文期刊>Journal of Medical Microbiology: An Official Journal of the Pathological Society of Great Britain and Ireland >First genetic evidence of Coxiella burnetii in cases presenting with acute febrile illness, India
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First genetic evidence of Coxiella burnetii in cases presenting with acute febrile illness, India

机译：印度急性发热疾病患者Coxiella Burnetii的第一个遗传证据

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摘要

Q fever is a worldwide zoonosis that is caused by Coxiellaburnetii, an obligate intracellular Gram-negative bacterium[1]. Infected domestic animals, particularly sheep, goats andcattle are the main sources of infection to humans [2]. Theorganism is shed in placentas, abortion products, urine, fae-ces and milk of infected animals. In humans, infection ismainly acquired via infective aerosols or contaminated dust[3]. Q fever is characterized by acute and chronic courses.Acute Q fever is often asymptomatic or manifests as a non-specific febrile, unrecognized illness [2]. Clinical presenta-tion of chronic Q fever includes vascular infections, bloodculture-negative endocarditis, osteoarticular involvementand chronic liver diseases [4]. Proper patient managementcan significantly reduce mortality due to chronic Q fever,making timely diagnosis of utmost importance. AlthoughC. burnetii causing acute febrile illness has been reportedworldwide [5, 6], its distribution in India is ill-defined.
机译：Q发烧是一个由Coxiellaburnetii引起的全球人群病，是一种迫使细胞内革兰氏阴性细菌[1]。受感染的家畜，特别是绵羊，山羊andcattle是对人类感染的主要来源[2]。在胎盘，堕胎产品，尿液，FAE-CES和感染动物牛奶中脱落。在人类中，通过感染气溶胶或受污染的粉尘获得感染才能获得[3]。 Q发烧的特征在于急性和慢性疗程。易患Q发热通常是无症状的或表现为非特异性发热，无法识别的疾病[2]。慢性Q发烧的临床表现包括血管感染，血液栽培阴性心内膜炎，骨质术中的参与和慢性肝疾病[4]。适当的患者ManagementCan由于慢性Q发烧显着降低死亡率，并及时诊断至关重要。虽然。已经报告了伯诸特菌导致急性发热疾病[5,6]，其在印度的分布不明显。

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