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首页> 外文期刊>RSC Advances >Structural characterization of a novel Lactarius volemus Fr. polysaccharide and its immunity activity in BALB/c mice
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Structural characterization of a novel Lactarius volemus Fr. polysaccharide and its immunity activity in BALB/c mice

机译：新型Lactarius voremus fr.的结构表征BALB / C小鼠的多糖及其免疫活性

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摘要

Lactarius volemus Fr. has been regarded as a great edible medicinal fungal resource in China. In this study, L. volemus Fr. polysaccharide (LVP) with an average molecular weight of 16.842 kDa was obtained by water extraction. The structure of LVP was characterized to be mannan, and the linkages in the mannan were found to comprise the Man p , (1→4)-α-Man and (1→4,6)-α-Man. Furthermore, intraperitoneal administration of LVP increased the thymus, spleen and liver indices, dose-dependently. Additionally, LVP enhanced the immune response and the phagocytic activities. Pathological evaluations showed that LVP in mice increased the proliferation of red medullary lymphocytes (60–70%). Collectively, these results indicated that LVP might be a potential resource of raw material for further investigations of functional foods.
机译：Lactarius valemus fr.已被视为中国的一个伟大的食用药用真菌资源。在这项研究中，L. Valemus Fr.通过水萃取得到平均分子量为16.842kDa的多糖（LVP）。 LVP的结构表征为人类，发现甘露甘露甘露甘露甘露甘露甘露甘露甘露甘露甘露甘露甘露甘露甘露甘露甘露甘露甘露甘露甘露甘露甘露甘露甘露甘露甘露甘露甘露甘露甘油此外，LVP腹膜内施用胸腺，脾脏和肝脏指数依赖性。此外，LVP增强了免疫应答和吞噬活动。病理评价表明，小鼠的LVP增加了红髓质淋巴细胞的增殖（60-70％）。总的来说，这些结果表明，用于进一步研究功能性食物的原料的潜在资源。

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