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Integrated microfluidic device for the spherical hydrogel pH sensor fabrication

机译:用于球形水凝胶pH传感器制造的集成微流体装置

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In this work, hydrogel photonic crystal beads with inverse opal structure are generated on a well-controlled microfluidic chip device. An online droplet drying method and templating technique are integrated into the producing process. This process results in the silica nanoparticles in the droplets self-assembled into spherical photonic crystals with narrow stop bands and identical structural colours, which is the ideal template for fabricating inverse opal hydrogel beads. The effects of acrylic acid (AA) concentration, water dosage and buffer pH on the equilibrium swelling of inverse opal hydrogel are discussed. In the concentration of AA (3%) and water (31%), the inverse opal hydrogel beads show wide sensing range and rapid response (less than 30 s) to pH variation. Overall, the inverse opal hydrogels as pH sensors show homogeneous structural colour changes due to the spherical 3D structure. The present characterization of quite mechanically robust and good reproducibility for the spherical pH sensor may have promise application in advanced optical devices.
机译:在这项工作中,在受良好控制的微流体芯片装置上产生具有反向蛋白石结构的水凝胶光子晶体珠。在线液滴干燥方法和模板技术集成到生产过程中。该方法导致液滴中的二氧化硅纳米粒子自组装成具有窄止动带和相同结构颜色的球形光子晶体,这是制造反蛋白石水凝胶珠的理想模板。讨论了丙烯酸(AA)浓度,水剂量和缓冲pH对反蛋白水凝胶平衡肿胀的影响。在AA(3%)和水浓度(31%)的浓度中,反蛋白水凝胶珠子显示出宽的感测范围和快速响应(小于30秒)至pH变异。总的来说,逆蛋白水凝胶作为pH传感器显示出由于球形3D结构而变化的均匀结构颜色。对球形pH传感器的非常机械稳健和良好再现性的本表征可以在先进的光学设备中具有承诺应用。

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