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A coordination and ligand replacement based three-input colorimetric logic gate sensing platform for melamine, mercury ions, and cysteine

机译:基于三次比色逻辑门传感平台的三聚氰胺,水银离子和半胱氨酸的协调与配体

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Discrimination of different species in various target scopes within a single sensing platform can provide many advantages such as simplicity, rapidness, and cost effectiveness. Here we design a three-input colorimetric logic gate, based on the aggregation and anti-aggregation of gold nanoparticles (Au NPs), for the sensing of melamine, cysteine, and Hg ~(2+) . The concept makes use of the advantages of the highly specific coordination and ligand replacement reactions between melamine, cysteine, Hg ~(2+) , and Au NPs. Different outputs are obtained with the combinational inputs in the logic gates, which can serve as a reference to discriminate different analytes within a single sensing platform. Furthermore, besides the intrinsic sensitivity and selectivity of Au NPs to melamine-like compounds, the “INH” gates of melamine/cysteine and melamine/Hg ~(2+) in this logic system can be employed for sensitive and selective detections of cysteine and Hg ~(2+) , respectively.
机译:在单个传感平台内各种目标范围的不同物种的歧视可以提供许多优点,例如简单,快速,成本效益。在这里,我们根据金纳米颗粒(Au NPS)的聚集和抗聚集,用于感测三聚氰胺,半胱氨酸和Hg〜(2+)的聚集和抗聚集,设计了三输入比色逻辑门。该概念利用三聚氰胺,半胱氨酸,Hg〜(2+)和Au nps之间的高度特异性协调和配体置换反应的优点。利用逻辑门中的组合输入获得不同的输出,其可以作为对单个传感器平台内的不同分析物的参考。此外,除了Au nps对三聚氰胺状化合物的内在敏感性和选择性,该逻辑系统中的三聚氰胺/半胱氨酸和三聚氰胺/ hg〜(2+)的“INH”型可以用于敏感和选择性检测半胱氨酸和Hg〜(2+)分别。

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