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A coordination and ligand replacement based three-input colorimetric logic gate sensing platform for melamine, mercury ions, and cysteine

机译:基于配位体和配体置换的三输入三聚氰胺,汞离子和半胱氨酸比色逻辑门传感平台

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摘要

Discrimination of different species in various target scopes within a single sensing platform can provide many advantages such as simplicity, rapidness, and cost effectiveness. Here we design a three-input colorimetric logic gate, based on the aggregation and anti-aggregation of gold nanoparticles (Au NPs), for the sensing of melamine, cysteine, and Hg2+. The conceptmakes use of the advantages of the highly specific coordination and ligand replacement reactions between melamine, cysteine, Hg2+, and Au NPs. Different outputs are obtained with the combinational inputs in the logic gates, which can serve as a reference to discriminate different analytes within a single sensing platform. Furthermore, besides the intrinsic sensitivity and selectivity of Au NPs to melamine-like compounds, the "INH" gates of melamine/cysteine and melamine/Hg2+ in this logic system can be employed for sensitive and selective detections of cysteine and Hg2+, respectively.
机译:在单个传感平台内的各种目标范围内对不同物种的区分可以提供许多优势,例如简单,快速和具有成本效益。在这里,我们基于金纳米颗粒(Au NPs)的聚集和反聚集,设计了一个三输入比色逻辑门,用于检测三聚氰胺,半胱氨酸和Hg2 +。该概念利用了三聚氰胺,半胱氨酸,Hg2 +和Au NP之间高度特异性的配位和配体置换反应的优势。通过逻辑门中的组合输入获得不同的输出,这些输入可以用作区分单个传感平台中不同分析物的参考。此外,除了Au NPs对三聚氰胺样化合物的固有敏感性和选择性外,该逻辑系统中三聚氰胺/半胱氨酸和三聚氰胺/ Hg2 +的“ INH”门可分别用于半胱氨酸和Hg2 +的灵敏和选择性检测。

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