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Rational design of a fluopyram hapten and preparation of bioconjugates and antibodies for immunoanalysis

机译:氟吡喃醇的合理设计,并制备免疫分析的生物缀合物和抗体

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A fluopyram hapten was designed in which insignificant electronic and structural modifications were foreseen and all potentially interacting chemical moieties were maintained. This hapten was prepared by total synthesis and three immunologically active bioconjugates were obtained and characterized. High-affinity and specific antibodies to fluopyram were raised.
机译:设计了一种博物馆Hapten,其中预先设计了微不足道的电子和结构修饰,并保持所有可能的相互作用的化学部分。该HAPTEN通过总合成制备,得到了三种免疫活性生物缀合物并表征。提高了对氟化罗仑的高亲和力和特异性抗体。

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