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首页> 外文期刊>Scientific reports. >Non-invasive continuous-time glucose monitoring system using a chipless printable sensor based on split ring microwave resonators
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Non-invasive continuous-time glucose monitoring system using a chipless printable sensor based on split ring microwave resonators

机译:非侵入式连续时间血糖监测系统,使用基于分流环微波谐振器的芯片可打印传感器

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This paper reports a highly sensitive, non-invasive sensor for real-time glucose monitoring from interstitial fluid. The structure is comprised of a chip-less tag sensor which may be taped over the patient’s skin and a reader, that can be embedded in a smartwatch. The tag sensor is energized through the established electromagnetic coupling between the tag and the reader and its frequency response is reflected on the spectrum of the reader in the same manner. The tag sensor consumes zero power as there is no requirement for any active readout or communication circuitry on the tag side. When measuring changes in glucose concentrations within saline replicating interstitial fluid, the sensor was able to detect glucose with an accuracy of?~?1?mM/l over a physiological range of glucose concentrations with 38?kHz of the resonance frequency shift. This high sensitivity is attained as a result of the proposed new design and extended field concentration on the tag. The impact of some of the possible interferences on the response of the sensor’s performance was also investigated. Variations in electrolyte concentrations within the test samples have a negligible effect on the response of the sensor unless these variations are supra-physiologically large.
机译:本文报道了一种高度敏感的非侵入性传感器,用于从间质性流体进行实时血糖监测。该结构包括芯片的标签传感器,其可以被粘贴在患者的皮肤和读取器上方,可以嵌入智能手表中。标签传感器通过标签和读取器之间的建立的电磁耦合通电,并且其频率响应以相同的方式反映在读取器的频谱上。标签传感器消耗零功率,因为​​标签侧的任何活动读数或通信电路都不要求。当测量盐水中的葡萄糖浓度的变化复制间质液时,传感器能够在具有38ΩkHz的葡萄糖浓度的葡萄糖浓度的生理范围内检测葡萄糖,其具有38ΩkHz的共振频率。由于标签上提出的新设计和扩展的场浓度,因此获得了这种高灵敏度。还研究了一些可能的干扰对传感器性能的响应的影响。在测试样品内的电解质浓度的变化对传感器的响应具有可忽略不计的影响,除非这些变化是对物理学上大的。

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