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首页> 外文期刊>Journal of Clinical and Diagnostic Research >High Grade Serous Carcinoma Presenting as a Huge Pelvic Mass with Normal Looking Ovaries: A Diagnostic Challenge for Pathologist
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High Grade Serous Carcinoma Presenting as a Huge Pelvic Mass with Normal Looking Ovaries: A Diagnostic Challenge for Pathologist

机译：高级浆液癌作为巨大的盆腔，正常看卵巢：病理学家的诊断挑战

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High-grade serous carcinoma represents 50-60% of all ovarian cancers and is the most common type of malignant surface epithelialtumour. Serous carcinoma is often diagnosed in the sixth and seventh decade, while the mean age for high-grade tumours is 63year. It’s not only the nonspecifc symptoms like vague abdominal pain, nausea, gastrointestinal disturbances, but also the unusualpresentation which is responsible for delayed diagnosis. This diagnostic delay can become the reason for increased mortality,despite advances in surgical management and chemotherapy. Here, we discuss a case of 60-year-old postmenopausal women whopresented with a huge pelvi-peritoneal mass and with grossly normal ovaries. Considering clinical fndings and histomorphology,the possibility of malignant mesothelioma was considered as the frst differential diagnosis; however extensive sampling of ovariesand supportive immunohistochemical markers helped us to arrive at a defnitive diagnosis. The present case emphasises theimportance of extensive tissue sampling and ancillary techniques in arriving at a correct diagnosis.
机译：高级浆液癌占所有卵巢癌的50-60％，是最常见的恶性肿瘤性肌肉肿瘤。浆液癌经常在第六和第七十年中被诊断，而高级肿瘤的平均年龄是63年。它不仅是模糊腹痛，恶心，胃肠道紊乱等非缺口症状，而且是对延迟诊断的不寻常的不寻常。尽管外科医疗和化疗进展，但这种诊断延迟可能成为死亡率增加的原因。在这里，我们讨论了60岁的绝经后妇女的案例，以巨大的骨盆腹膜和卵巢巨大的卵巢。考虑到临床FNDING和组织，恶性间皮瘤的可能性被认为是FRST差异诊断;然而，广泛的卵巢和支持性免疫组织化学标记的采样有助于我们达到一种缺陷诊断。目前的案例强调了在达到正确诊断时的广泛组织采样和辅助技术的推动。

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