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首页> 外文期刊>Journal of Clinical and Diagnostic Research >A Clinicopathological Analysis and Functional Outcomes of Claviculectomy in Primary Malignant Tumours of Clavicle
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A Clinicopathological Analysis and Functional Outcomes of Claviculectomy in Primary Malignant Tumours of Clavicle

机译：锁骨原发性恶性肿瘤临床病理分析及克拉夫乳切除术的临床病理分析

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Primary malignant tumours of the clavicle are exceptionally uncommon. In the literature the number of publications reporting long-term oncologic outcomes after claviculectomy is quite low.Aim: To analyse clinicopathological presentation of functional results of 15 patients with primary malignant clavicular tumour after claviculectomy and also to evaluate relationship of resection amount and the postoperative complication state with functional results.Materials and Methods: Fifteen patients (9 males, 6 females; mean age 44.8 years; range 2-87 years) with primary malignant tumours of clavicle who were performed claviculectomy between 2002 and 2017 were included the study. Patient’s mean follow-up duration was 41 months (range 14 to 68 months). Twelve patients underwent partial and 1 patient underwent total clavicle resection without reconstruction. Two patients underwent reconstruction with allograft fibula after partial clavicle resection. The functional result was assessed with the Constant-Murley scores, International Society of Limb Salvage-Musculoskeletal Tumour Society (MSTS) evaluation system and The University of California-Los Angeles (UCLA) shoulder rating scale. Mann Whitney u test was used for comparison of data sets. Spearman correlation was used to test the association between resection amount and patient’s scale scores. Linear regression analyses were carried out to evaluate the association of resection amount with patient’s scale scores.Results: The mean postoperative MSTS score was 63.1±14.1 (range, 33-80), the mean Constant-Murley score was 57.8±13.7 (range, 30-74) and the mean UCLA score was 20.8±6.8 (range, 8-31). A statistically significant and perfect negative corelation was found between resection amount and MSTS score (r=-0.907 p<0.001), Constant-Murley score (r=-0.910, p<0.001) and UCLA score (r=-0.975, p<0.001). It has been found that resection amount was significantly higher in the patients with complication than in the patients without complication (p=0.005), and MSTS score (p=0.014), Constant-Murley score (p=0.026) and UCLA score (p=0.007) were significantly lower.Conclusion: The present study concluded that the extent of claviculectomy resection has an effect on shoulder functions. Although the shoulder functional scores were found to be ow, patient’s daily activities were affected minimally. Beside, reconstruction has not been suggested due to the high rates of complications.
机译：锁骨的原发性恶性肿瘤是异常罕见的。在文献中，报告克拉夫霉菌切除术后长期肿瘤结果的出版物的数量相当低。目的：分析克拉维术后原发性恶性锁骨瘤患者功能结果的临床病理学呈递，并评估切除率的关系和具有功能性结果的术后并发症状态。材料和方法：十五名患者（9名男性，6名女性;平均年龄为44.8岁; 2-87岁），2002年至2017年之间进行克拉夫氏菌的原发性恶性肿瘤锁骨切除术包括该研究。患者的平均随访时间为41个月（范围为14至68个月）。 12名患者接受了部分和1例患者在没有重建的情况下接受过总锁骨切除。两次患者接受分类纤维后重建的部分锁骨切除后。通过恒门分数，国际肢体爆炸 - 肌肉骨骼肿瘤会（MSTS）评估体系和加州大学 - 洛杉矶（UCLA）肩标评定规模，评估了功能结果。 Mann Whitney U测试用于比较数据集。 Spearman相关性用于测试切除量和患者的规模分数之间的关联。进行了线性回归分析，以评估切除量与患者的规模评分的结合。结果：平均术后MSTS得分为63.1±14.1（范围，33-80），平均恒定的Murley评分为57.8±13.7 （范围，30-74）和平均的UCLA得分为20.8±6.8（范围，8-31）。切除量和MSTS评分（r = -0.907 p <0.001）之间发现了统计学上显着和完美的阴性必序（r = -0.910，p <0.001）和ucla得分（r = -0.975，p < 0.001）。已经发现，在没有并发症的患者的患者中，切除术患者显着较高（P = 0.005）和MSTS评分（P = 0.014），恒村评分（P = 0.026）和UCLA得分（P = 0.007）显着降低。结论：本研究得出结论，克拉夫乳切除切除术的程度对肩部功能有影响。虽然发现肩部功能分数是欠，但患者的日常活动很小。除此之外，由于并发症的高率，尚未建议重建。

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