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首页> 外文会议>Academic Committee conference of Shanghai key lab of stomatology >Malignant transformation of oral epithelial dysplasia: clinicopathological risk factors and outcome analysis in a retrospective cohort of 138 cases
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Malignant transformation of oral epithelial dysplasia: clinicopathological risk factors and outcome analysis in a retrospective cohort of 138 cases

机译：回顾性队列138例口腔上皮异常增生恶性转化的临床病理危险因素及结局分析

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@@ Aims: To explore the usefulness of a new binary system of grading dysplasia proposed by the World Health Organization and to identify significant risk factors for malignant transformation in a long-term follow-up cohort of patients with oral epithelial dysplasia. Methods and results: A total of 138 patients with histologically confirmed oral dysplasia between 1978 and 2008 were reviewed retrospectively in our department. The mean follow-up period was 5.1 years. Of these dysplasias. 37 (26.8%) developed into cancer, with a mean duration of 4.6 years. Cox regression analysis revealed that high-grade dysplasia was an independent risk factor for transition, but age, gender, lesion site, diet habit, smoking and alcohol intake were not risk factors.
机译：目的：探讨由世界卫生组织提出的新的分级异型增生二元系统的实用性，并确定长期随访的口腔上皮异型增生患者恶性转化的重要危险因素。方法与结果：回顾性分析1978年至2008年间经组织学证实为口腔发育不良的138例患者。平均随访期为5。1年。这些不典型增生。 37名（26.8％）患癌，平均病程4.6年。 Cox回归分析显示，高度不典型增生是过渡的独立危险因素，但年龄，性别，病变部位，饮食习惯，吸烟和饮酒不是危险因素。

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