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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Elusive Presentations of Female Genital Tuberculosis: A Case Series
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Elusive Presentations of Female Genital Tuberculosis: A Case Series

机译：难以捉摸的女性生殖结核术语：案例系列

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The Ministry of Health and Family Welfare has made a target of eliminating tuberculosis by 2025 under the National Tuberculosis Elimination Plan (NTEP). For this, it is important to identify cases, notify and treat them effectively. This case series is on women with unique presentations of the Female Genital Tract TB (FGTB). It further explores the diagnostic and treatment modalities of such cases. The cases include four women with atypical presentations- a young nulliparous woman with repeated episodes of pyometra, a woman with tubo-ovarian mass and chronic fever and two women with adnexal masses mimicking dermoid and endometriosis, respectively. The diagnosis was based on the unique presentations, exclusion of other diseases and on the operative findings. One should target to get a tissue based diagnosis. Now the government has advised Cartridge-Based Nucleic Acid Amplification Test (CBNAAT), for all samples of FGTB, to get an accurate estimation of drug resistance. It can be used in very interior areas, gives a result within the same day and also gives sensitivity results to the antitubercular drugs. CBNAAT may give incorrect results with small specimens. That makes clinical judgement by specialists very important. The antitubercular regime has changed and there are no separate regimes for relapses or treatment failures. It is now therapy with daily intake of rifampicin, isoniazid, pyrazinamide and ethambutol for two months and rifampicin, isoniazid and ethambutol for four months. For all cases of FGTB, a working definition should be given and notification should be done by the Nikshay online portal. Future structured studies are required to investigate the sensitivity and specificity of different tissues for CBNAAT in different clinical scenarios of genital Tuberculosis (TB).
机译：卫生和家庭福利部在国家结核病消除计划（NTEP）下，在2025年下消除了结核病的目标。为此，重要的是要识别案件，有效地通知和治疗它们。本案例系列是女性，具有雌性生殖器TB（FGTB）的独特介绍。它进一步探讨了这种情况的诊断和治疗方式。这些案件包括四名有非典型介绍的妇女 - 一个年轻的无污染妇女，其中一名患有Pyometra的重复发作，一个有Tubo-卵巢质量和慢性发热的妇女，分别模仿Dermoid和子宫内膜异位症。诊断基于独特的演示，排除其他疾病以及操作结果。一个人应该靶向基于组织的诊断。现在，政府已经建议了基于墨盒的核酸扩增试验（CBNAAT），用于所有FGTB样品，以获得准确估计耐药性。它可以在非常内部区域使用，在同一天给予结果，并给予抗核药物的敏感性结果。 CBNAAT可能会使小标本产生不正确的结果。这使得专家临床判断非常重要。抗真正制度发生了变化，没有分开的重复或治疗失败的制度。现在是每天摄入利福平，异烟肼，吡嗪酰胺和乙胺丁醇治疗两个月和利福平，异烟肼和乙胺丁醇四个月。对于所有FGTB的情况，应给予工作清晰度，并通过Nikshay Online Portal进行通知。未来的结构研究是探讨CBNAAT不同组织的敏感性和特异性在生殖器结核病（TB）的不同临床情景中。

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