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首页> 外文期刊>Journal of Clinical and Diagnostic Research >An Interesting Case of Rhino-Orbito-Cerebral Mucormycosis: A Case Report
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An Interesting Case of Rhino-Orbito-Cerebral Mucormycosis: A Case Report

机译：rhino-oritbo-脑粘膜粘膜菌病的有趣情况：案例报告

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Fungal infections are the most challenging problems in an immunocompromised individual. Mucormycosis is a life-threatening fungal infection with rapid progression and high mortality in immunocompromised individuals. A case of 58-year-old female, with uncontrolled diabetes is with five days history of headache, fever, and acute onset drooping of the eyelid. The initial vision was normal which dropped to PL in the following days, with ophthalmoplegia and dilated nonreactive pupil in the right eye. Fundus and IOP were normal on presentation. MRI and MRV brain showed subtle ethmoidal cysts. CT-PNS showed mild ethmoidal thickening and cyst. Diagnostic nasal endoscopy showed unhealthy mucosa with no lesion suggesting eschar. A provisional diagnosis of orbital mucormycosis was made. The patient was started on antibiotics and IV Amphotericin B but she went on to further neurological complications. Despite treatment, she developed necrotising eschars in eyelid for which debridement was done. Further, exenteration was advised and patient developed septicaemia, however he died. The culture from debrided tissue showed growth of mucor. The objective of presenting this particular case is to emphasise the importance of considering mucormycosis as diagnosis despite subtle radiological and endoscopic findings in symptomatic immunocompromised patients. Early diagnosis and aggressive management improve better chances for survival.
机译：真菌感染是免疫构成个人中最具挑战性的问题。粘膜霉病是一种危及生命的真菌感染，免疫性血肿性质的快速进展和高死亡率。 58岁女性的案例，不受控制的糖尿病是有五天的头痛，发烧和急性发作的眼睑下垂。初始视觉正常在下面的末期下降到PL，用眼科剧集和右眼扩张的非反应瞳孔。眼底和IOP在介绍时正常。 MRI和MRV脑显示出微妙的符号囊肿。 CT-PNS显示出轻度血管增稠和囊肿。诊断鼻内镜检查显示不健康的粘膜，没有病变表明ESCHAR。制备了轨道粘膜霉菌的临时诊断。患者在抗生素和IV两性霉素B上开始，但她继续进一步的神经系统并发症。尽管待遇，但她在眼睑中发育了坏死的eSchars，为其进行了清理。此外，建议出门，患者发育败血症，但他死亡。来自脱击组织的培养表现出粘膜的生长。展示这种特殊情况的目的是强调考虑粘液霉病作为诊断的重要性，尽管在症状免疫功能性患者中细微放射和内窥镜发现。早期诊断和侵略性管理提高了生存的更好机会。

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