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首页> 外文期刊>Case Reports in Pediatrics >Arrested Puberty in an Adolescent Male with Anorexia Nervosa Successfully Resumed with Multidisciplinary Care
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Arrested Puberty in an Adolescent Male with Anorexia Nervosa Successfully Resumed with Multidisciplinary Care

机译：厌食症中的青少年男性在青少年患有多学科护理恢复

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The normal development of puberty depends on the specific pulsatility of gonadorelin, which is finely regulated by genetic and environmental factors. In the published literature, eating disorders figure as a cause of pubertal delay/arrest in females but are rarely considered in males with disordered puberty. A 16.7-year-old male was referred to the Department of Pediatrics with arrested puberty due to severe malnutrition in the context of food restriction. Past medical history was relevant for asthma. Generalized cachexia, facial lanugo hair, cutaneous xerosis, and Russell’s sign were noted; he had a height of 155.5?cm (?2.5 SD; target height: 168?cm, ?1.1 SD) and a BMI of 12.4?kg/m 2 (?6.8 SD); left and right testicular volumes were 8?mL and 10?mL, respectively. He had a twin brother who had normal auxological/pubertal development (height: 167?cm, ?1.05 SD; testicular volumes: 20?mL). Anorexia nervosa was diagnosed, and he was enrolled in a personalized treatment and surveillance program. “Nonthyroid illness” resembling secondary hypothyroidism was noted, as was low bone mineral density. Clinical and biochemical follow-up showed significant improvements in BMI (16.2?kg/m 2 , ?2.55 SD), completion of puberty (testicular volumes: 25?mL), and reversion of main neuroendocrine abnormalities. Herein, we present an adolescent male with arrested puberty in the context of anorexia nervosa. The recognition of this rare condition in males allows a personalized approach to disordered puberty, with resumption of normal function of the hypothalamic-pituitary-gonadal axis and achievement of pubertal milestones.
机译：青春期的正常发展取决于促性腺素的特异性脉动，其被遗传和环境因素精细调节。在发表的文献中，饮食障碍人物作为女性的青春期延迟/逮捕的原因，但很少在雌性失调的青春期中考虑。由于在食品限制背景下，由于严重的营养不良，16.7岁的男性被称为Puberty的儿科部门。过去的病史与哮喘相关。指出了一般性的恶毒症，面部羊毛发，皮肤血症和拉塞尔的标志;他的高度为155.5？2.5 sd;目标高度：168？cm，？1.1 sd）和12.4 kg / m 2的bmi（？6.8 sd）;左和右睾丸体积分别为8？mL和10？ml。他有一个患有正常的疾病/青春期发育的双胞胎兄弟（高度：167？cm，？1.05 SD;睾丸量：20？ml）。厌食症神经组织被诊断出来，他参加了个性化的待遇和监督计划。 “非羟基氏疾病”已注意到继发性甲状腺功能减退症，低骨矿物密度低。临床和生化后续随访显示BMI的显着改善（16.2？kg / m 2，？2.55 sd），青春期完成（睾丸量：25μm），以及主要神经内分泌异常的逆转。在此，我们在厌食症神经系统的背景下呈现了一种青春期的青春期。对男性这种罕见病症的认识允许令人个性化的青春期进行个性化方法，恢复下丘脑 - 垂体 - 性腺轴的正常功能以及普格塔尔里程碑的成就。

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