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首页> 外文期刊>Case Reports in Ophthalmological Medicine >A New Rapidly Growing Dome-Shaped Choroidal Lesion in an Eye with Treated Retinoblastoma
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A New Rapidly Growing Dome-Shaped Choroidal Lesion in an Eye with Treated Retinoblastoma

机译：一种新的快速生长圆顶形脉络膜病变，眼睛治疗视网膜母细胞瘤

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Background . To describe an extensive untreatable choroidal metastasis by retinoblastoma in the treated patient which was clinically indistinguishable from regular tumor recurrence. Methods . A 24-month-old girl without a family history of retinoblastoma (RB) was discovered to have group C RB in her right eye and group D in her left eye. The patient received 12 cycles of intravenous chemotherapy, intra-arterial chemotherapy (IAC), and intravitreal chemotherapy for the left eye and focal adjuvant therapy (laser thermotherapy and cryotherapy) for both eyes. Six months after the last treatment, fundus examination showed a regressed tumor in both eyes. Ten months after the last treatment, except for in addition to tumor recurrence, rising intraocular pressure was noticed in the left eye. While doing IAC for the left eye, a very rapid growing yellowish dome-shaped mass was found which had doubled in size in two weeks. Enucleation was considered for her. Results . Pathology evaluation of the enucleated eye revealed a very massive dome-shaped choroidal metastasis invasion with poorly differentiated RB tumor. Prophylactic systemic chemotherapy was performed for the patient. Conclusion . Choroidal metastasis in RB patients is often diagnosed based on pathology reports, but it may rarely be seen in clinical examinations especially if the pattern of tumor recurrence and growth is abnormal.
机译：背景 。通过治疗患者的视网膜母细胞瘤描述一种广泛的无法治疗的脉络膜转移，其从常规肿瘤复发中临床上难以区分。方法 。一个没有视网膜母细胞瘤（RB）家族史的24个月大的女孩在她的右眼和左眼中群体群体CRB。患者接受了12个静脉内化疗，动脉内化疗（IAC）和椎管内化疗，对左眼和局灶性辅助治疗（激光热疗和冷冻疗法）的玻璃体内化疗进行静脉化疗。最后一次治疗后六个月，眼底检查在双眼中显示出了肿瘤。最后一次治疗后十个月，除了肿瘤复发之外，左眼上升的眼压上升。在为左眼进行IAC而进行IAC，发现淡黄色的淡黄色圆顶形状的肿块在两周内为大小翻倍。为她考虑了enucleation。结果 。生理学评估肌肉的术语揭示了一种具有差异差异差异差异的巨大圆顶形状脉络膜转移侵袭。对患者进行预防性全身化疗。结论 。 RB患者的脉络膜转移通常是基于病理报告诊断的，但在临床检查中可能很少见到临床检查，特别是如果肿瘤复发和生长的模式异常。

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