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Single dose of testosterone in children with hypospadias: any effect on the diameter of the glans penis?

机译:单剂量患儿患儿患有腹盆裂解的睾酮:对龟头阴茎直径的任何影响?

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Background:The purpose of this study was to assess the effect of a single dose of testosterone on the diameter of the glans penis.MethodsThis was a prospective evaluation of the effect of a single dose of testosterone on the diameter of the glans penis of children with hypospadias. The diameter of the glans penis was measured transversely at the level of the coronal sulcus using Vernier calipers. The patients were categorized into two groups: Group A and Group B. Group A received intramuscular testosterone at the dose of 2?mg per kilogram body weight. Group B did not receive any testosterone and served as control. The diameter of the glans penis was evaluated at the beginning of the study and at 4?weeks after the testosterone injection.ResultsOverall, 64 patients were evaluated. There were 32 patients in group A (50%) and 32 patients in group B (50%). The mean diameter in group A before and after testosterone injection was 17.6?mm?±?2.5 SD and 17.8?±?2.3 SD, respectively. The mean diameter in group B at onset and after 4?weeks was 17.6?mm?±?2.4 SD and 17.7?±?2.4 SD, respectively. p?=?0.12 which is statistically insignificant.ConclusionSingle dose of testosterone in children with hypospadias does not produce significant increase in the diameter of the glans penis.
机译:背景:本研究的目的是评估在龟头penis.MethodsThis的直径睾酮单剂量的效果的睾酮对龟头的直径单剂量的效果的前瞻性评价儿童的阴茎尿道下裂。阴茎龟头的直径在使用游标卡尺冠状沟的水平横向测量。将患者分为两类:A组和B组A组以2mg每千克体重剂量肌内接收睾酮。 B组未接受任何睾酮和作为对照。龟头的直径在研究开始时进行了评估,并在睾酮injection.ResultsOverall后4?周,64例患者进行了评价。有32例A组(50%)和32名患者在B组(50%)。在A组的平均直径之前和睾酮注射后为17.6?毫米?±?分别为2.5 SD和17.8?±?2.3 SD。在发作和4?周后,B组的平均直径为17.6?毫米?±?分别为2.4 SD和17.7?±?2.4 SD。 P 的?=?0.12是统计学insignificant.ConclusionSingle剂量的睾酮小儿尿道下裂不产生的阴茎龟头的直径显著增加。

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