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Comparative assessment of polyphenolics’ content, free radicals’ scavenging and cellular antioxidant potential in apricot fruit

机译:多酚含量的比较评估,杏果中的自由基扫干和细胞抗氧化潜力

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Natural antioxidants possess health beneficial properties and are being substantially used in foods, cosmetics and pharmaceutical products. Polyphenolics content, antioxidant activity and HepG2 liver cancer cells’ inhibition potential were determined and compared in the fruit of apricot cultivars collected from lower Himalayan region of Pakistan using standard analytical procedures. Comparatively, fruit of AP3 cultivar had highest levels of total phenolics and total flavonoids contents (220.5?±?15.9?mgGAE/100?g and 382.0?±?18.0 mgQE/100?g, respectively) on fresh weight basis. Fruit of the same cultivar had maximum DPPH scvenging potential (94.24?±?4.55%), oxygen radicals absorbance capacity at 4.71?±?0.12 mMolTE/100?g and inhibition of HepG2 cancer cells (45.80?±?4.01?μMolQE/100?g). Though, fruit of AP4 cultivar was rich in vanillic acid, caffeic acid, vanillin, epi-catechin and quercetin, but had relatively low antioxidant and anticancer potential. Disparities in the phytochemical composition and properties of apricot fruit are attributed to genetic differences and growing conditions. Total phenolics, total flavonoids and caffic acid depicted highly significant positive association (?90%) with ORAC, CAA and FRAP. Our findings suggest that being a rich source of health beneficial secondary metabolites, apricot fruit of Himalayan region of Pakistan could contribute considerably in socio-economic development of the local communities and as a functional food in regional and global markets.
机译:天然抗氧化剂,具有健康有益的特性,并且在食品,化妆品和医药产品基本上使用。多酚含量,抗氧化活性和HepG2肝癌细胞的抑制潜力进行了测定,并使用标准分析程序从巴基斯坦的下部喜马拉雅地区收集杏品种的果实相比较。相比较而言,AP3品种果有总酚,总类黄酮含量的最高水平(220.5?±?15.9?mgGAE / 100→克和382.0?±?18.0 mgQE / 100→克,分别地)在鲜重基础。同一品种的果实有最大DPPH scvenging电位(94.24?±4.55%),氧自由基吸收能力在4.71?±0.12 mMolTE / 100→克和HepG2肿瘤细胞的抑制(45.80?±4.01?μMolQE/ 100 ?G)。虽然,AP4品种的水果富含香草酸,咖啡酸,香草醛,表儿茶素和槲皮素,但具有相对低的抗氧化和抗癌的潜力。在植物化学物质的组合物差异和杏果的性质归因于遗传差异和生长条件。总酚,总黄酮和caffic酸描绘与ORAC,CAA和FRAP高度显著正相关(?90%)。我们的研究结果表明,是一个丰富的健康是有益的次生代谢产物的来源,巴基斯坦的喜马拉雅地区的杏果可大大当地社区的社会经济发展,并在区域和全球市场的功能性食品做出贡献。

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