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首页> 外文期刊>Journal of Ophthalmology >Combined Low-Level Light Therapy and Intense Pulsed Light Therapy for the Treatment of Dry Eye in Patients with Sj?gren’s Syndrome
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Combined Low-Level Light Therapy and Intense Pulsed Light Therapy for the Treatment of Dry Eye in Patients with Sj?gren’s Syndrome

机译：综合低级光疗法和激烈的脉冲光疗法治疗SJ患者干眼症患者的综合征

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Purpose . To evaluate the effects of combined intense pulsed light therapy (IPL) and low-level light therapy (LLLT) in dry eye disease (DED) in patients affected by Sj?gren’s syndrome. Patients and Methods . This is a monocentric, prospective, interventional study. At baseline, all the study patients ( n ?=?20) were on tear substitute therapy and underwent Schirmer type-1 test and breakup time (BUT) test. After baseline measurements, tear substitute therapy was suspended, and patients underwent IPL and LLLT. The same investigations were carried out at one (T1) and at three (T3) months after treatment. The Ocular Surface Disease Index (OSDI) survey was used to measure the severity of DED. Results . BUT test showed an increase in tear film breakup time in patients with DED 1 month after the beginning of the treatment (T0 vs T1: ). This increase was even more statistically significant after 3 months of the IPL and LLLT treatment (T0 vs T3: ). Schirmer test values increased too, but there was not statistically significance between values at T0 and T1 or T3. The patients perceived an improvement in their condition, which resulted in a lower score on the OSDI survey. The OSDI score was lower at T1 than T0 (T0 vs T1: ), while it tended to increase again after 3 months although it was still lower than baseline (T0 vs T3: ). No facial or ocular side effects were reported. Conclusions . The use of combined IPL/LLLT for the treatment of DED in patients affected by Sj?gren’s syndrome appears to be beneficial.
机译：目的 。评估受SJ影响的患者干眼症（DED）组合强烈脉冲光治疗（IPL）和低水平轻疗（LLLT）的影响吗？GREN综合征。患者和方法。这是一项单眼，前瞻性的介入研究。在基线时，所有的研究患者（N？=？20）都在撕裂替代治疗和接受Shirmer型测试和分解时间（但）测试。在基线测量后，悬浮替代治疗被暂停，并且患者接受了IPL和LLLT。在治疗后三（T1）和三（T3），在治疗后三次（T3）进行相同的研究。眼部疾病指数（OSDI）调查用于衡量DED的严重程度。结果 。但测试表明，治疗开始后的DED 1个月患者的泪膜破碎时间增加（T0 VS T1：）。在IPL和LLLT治疗3个月后，这种增长甚至更明显（T0 VS T3：）。 Schirmer测试值也增加，但T0和T1或T3的值之间没有统计学意义。患者感受到其状况的改善，导致OSDI调查中的得分较低。 T1的OSDI评分低于T0（T0 VS T1：），而3个月后它往往再次增加，尽管它仍然低于基线（T0 Vs T3：）。没有报告面部或眼部副作用。结论。使用合并的IPL / LLLT用于治疗受SJ影响的患者的治疗？GREN的综合征似乎是有益的。

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