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首页> 外文期刊>Journal of Ophthalmology >Cataract Surgery with or without Intraocular Lens Implantation in Pediatric Uveitis: A Systematic Review with Meta-Analyses
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Cataract Surgery with or without Intraocular Lens Implantation in Pediatric Uveitis: A Systematic Review with Meta-Analyses

机译：具有或没有人工晶状体植入在儿科葡萄膜炎的白内障手术：用Meta-Analyzes进行系统审查

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Purpose . To systematically review the results of comparative studies of modern cataract surgery in pediatric uveitis with or without intraocular lens (IOL) implantation and to perform comparative meta-analyses to compare visual acuity outcomes and complication rates. Methods . On 12 November 2020, we systematically searched the Cochrane Central, PubMed/MEDLINE, EMBASE, ClinicalTrials.gov, and all affiliated databases of the Web of Science. Two authors independently reviewed studies and extracted data. Studies were reviewed qualitatively in text and quantitatively with meta-analyses. Outcome measures were preoperative and postoperative best-corrected visual acuity (BCVA), inflammation control, and rates of postoperative complications. Results . Ten studies of 288 eyes were eligible for review of which the majority were eyes with juvenile idiopathic arthritis-associated uveitis. Summary estimates revealed that the BCVA was better in pseudophakic eyes vs. aphakic eyes (1-year postoperative: ?0.23 logMAR, 95% CI: ?0.43 to ?0.03 logMAR, ; 5-year postoperative: ?0.35 logMAR, 95% CI: ?0.51 to ?0.18 logMAR, ). Pseudophakic eyes had more visual axis opacification (OR 6.76, 95% CI: 2.73 to 16.8, ) and less hypotony (OR 0.19, 95% CI: 0.04 to 0.95, ). Conclusions . In modern era cataract surgery on eyes with pediatric uveitis with IOL implantation leads to satisfactory and superior visual outcomes and no differences in complication rates apart from an increased prevalence of visual axis opacification and a decreased prevalence of hypotony when compared to aphakia. However, limitations of the retrospective design and the presence of selection bias necessitate a careful interpretation.
机译：目的 。为了系统地审查有或没有人工晶体（IOL）植入儿童葡萄膜炎现代白内障手术的比较研究的结果，并进行比较的荟萃分析比较视力结果和并发症的发生率。方法 。在2020年11月12日，我们系统地搜查了科克伦中央，考研/ MEDLINE，文摘，ClinicalTrials.gov和Web of Science中的所有关联的数据库。两位作者独立评审，并提取数据。研究进行荟萃分析定性文字和定量审查。成果的措施，术前和术后最佳矫正视力（矫正视力），炎症控制，及术后并发症的发生率。结果 。 288眼10项研究进行资格复审，其中大部分是眼睛幼年特发性关节炎相关的葡萄膜炎。摘要估计表明，最佳矫正视力好于人工晶状体眼与无晶状体眼（1年期术后：0.23的logMAR，95％CI：0.43〜0.03的logMAR，5年术后：？？？？0.35的logMAR，95％CI： ？0.51〜0.18的logMAR）。人工晶状体眼有更多的视轴混浊（OR 6.76，95％CI：2.73至16.8，）和更少的低眼压（OR 0.19，95％CI：0.04〜0.95）。结论。在眼睛上的现代时代白内障手术人工晶状体植入导致令人满意，出色的视觉效果小儿葡萄膜炎和来自视轴区浑浊的发病率增加和在并发症的发生率除了没有差异相比，无晶状体眼时降低低眼压的发生率。然而，回顾性设计和选择偏差的存在的局限性必要仔细解释。

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