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首页> 外文期刊>Open Journal of Nephrology >Prevalence of Severe Anemia (Hb ≤ 5 g/dl) in Non-Dialyzed Chronic Renal Failure Patients in the Nephrology and Hemodialysis Department of Point G University Hospital
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Prevalence of Severe Anemia (Hb ≤ 5 g/dl) in Non-Dialyzed Chronic Renal Failure Patients in the Nephrology and Hemodialysis Department of Point G University Hospital

机译：肾病大学医院肾病和血液透析系重症贫血（HB≤5g/ dl）的患病率

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Introduction: Chronic renal failure (CRF) is defined as glomerular filtration rate (GFR) less than 60 ml/min/1.73m~(2) for at least three (3) months. Anemia is one of its most common complications. Anemia increases the risk factor for cardiovascular mortality by 18% per gram of hemoglobin loss. Objectives: To determine the prevalence and characteristics of this severe anemia, to determine the indications for transfusion, the complications related to this anemia, the evolution and the prognosis of these patients. Materials and Methods: This was a descriptive study with retrospective data collection over 18 months (January 1, 2017 to June 30, 2018) that included hospitalized CRF patients. Were included, non-dialyzed chronic renal failure patients with Hb ≤ 5 g/dl hospitalized during the said period. Not included were chronic renal failure patients with an Hb level ≥ 5 g/dl, those followed up and/or hospitalized outside the study period. Results: Among 1176 patients, 26 had severe anemia (Hb level ≤ 5 g/dl) on CRF, a prevalence of 2.21%. The mean age was 40 years ± 32.62 with extremes of 15 and 67 years. Seventeen women and 9 men. The etiology of chronic renal failure (CRF) was hypertensive vascular nephropathy in 50% of cases. CRF was end-stage in 18 patients (69.2%). The mean hemoglobin level was 4.10 g/dl ± 0.64 with extremes of 2 and 5 g/dl. The anemia was microcytic hypochromic in 50% and aregenerative (96.2%). The main symptoms were asthenia in 20 cases (76.9%), dizziness in 20 cases (76.9%), exertional dyspnea in 19 cases (73.1%). Signs of cardiac decompensation (n = 12) were jugular turgor 10 cases (38.5%), hepato-jugular reflux 06 cases (23.1%), mitral insufficiency murmur 06 cases (23.1%). The main complication was left ventricular hypertrophy 17 cases (77.3%). There was no correlation between anemia and sex (p = 0.291), age (p = 0.778), malaria (p = 0.158), etiology of CRF (p = 0.26). The evolution after treatment of anemia was favorable in 19 patients (73.1%), unfavorable in 02 patients (7.7%) and 05 deaths (19.2%). The deaths were of cardiovascular cause: left ventricular insufficiency 04 cases, stroke 01 case. Conclusion: Anemia is frequent in patients with chronic renal failure and remains an important risk factor for cardiovascular disease and poor general condition.
机译：介绍：慢性肾功能衰竭（CRF）定义为小于60ml / min / 1.73m〜（2）的肾小球过滤速率（GFR）至少为三（3）个月。贫血是其最常见的并发症之一。贫血将心血管死亡率的危险因素增加18％，每克血红蛋白损失为18％。目的：确定这种严重贫血的患病率和特征，确定输血的适应症，与这种贫血相关的并发症，这些患者的进化和预后。材料和方法：这是一个有超过18个月（2017年1月1日至2018年6月30日）的回顾性数据收集的描述性研究，包括住院患者的CRF患者。包括在内，非透析的慢性肾功能衰竭患者≤5g/ dl在所述期间住院。不包括慢性肾功能衰竭患者≥5g/ dl，那些随访和/或在研究期间住院。结果：在1176名患者中，CRF的26例严重贫血（HB含量≤5g/ dl），患病率为2.21％。平均年龄为40年±32.62，极端为15和67岁。十七名女性和9名男子。慢性肾功能衰竭（CRF）的病因在50％的病例中是高血压血管肾病。 CRF是18名患者的终末期（69.2％）。平均血红蛋白水平为4.10g / dl±0.64，极端为2和5g / dl。贫血是50％的微细肾上腺素，较高（96.2％）。主要症状在20例（76.9％），20例（76.9％）的头晕（76.9％），19例患病（73.1％）。心脏失代偿的迹象（n = 12）是颈静脉10例（38.5％），肝杂草回流06例（23.1％），二尖瓣不足杂音06例（23.1％）。主要并发症是左心室肥大17例（77.3％）。贫血和性别之间没有相关性（p = 0.291），年龄（p = 0.778），疟疾（p = 0.158），CRF的病因（p = 0.26）。治疗贫血后的演变是有利的19名患者（73.1％），在02名患者中不利（7.7％）和05例死亡（19.2％）。死亡人数是心血管原因：左心室不足04例，中风01例。结论：贫血在慢性肾功能衰竭患者中经常出现，仍然是心血管疾病的重要危险因素和差的一般情况。

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