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首页> 外文期刊>European respiratory review >Measuring pulmonary function in COPD using quantitative chest computed tomography analysis
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Measuring pulmonary function in COPD using quantitative chest computed tomography analysis

机译：使用定量胸部计算断层扫描分析测量COPD中的肺功能

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摘要

COPD is diagnosed and evaluated by pulmonary function testing (PFT). Chest computed tomography (CT) primarily serves a descriptive role for diagnosis and severity evaluation. CT densitometry-based emphysema quantification and lobar fissure integrity assessment are most commonly used, mainly for lung volume reduction purposes and scientific efforts. A shift towards a more quantitative role for CT to assess pulmonary function is a logical next step, since more, currently underutilised, information is present in CT images. For instance, lung volumes such as residual volume and total lung capacity can be extracted from CT; these are strongly correlated to lung volumes measured by PFT. This review assesses the current evidence for use of quantitative CT as a proxy for PFT in COPD and discusses challenges in the movement towards CT as a more quantitative modality in COPD diagnosis and evaluation. To better understand the relevance of the traditional PFT measurements and the role CT might play in the replacement of these parameters, COPD pathology and traditional PFT measurements are discussed.
机译：通过肺功能测试（PFT）诊断和评估COPD。胸部计算机断层扫描（CT）主要为诊断和严重程度评估提供描述性的作用。基于CT密度测定的肺气肿定量和洛洛裂缝完整性评估最常用，主要用于肺粪积减少目的和科学努力。朝向CT评估肺功能的更加定量作用的转变是逻辑下一步，因为当前未结束，信息存在于CT图像中。例如，可以从CT中提取肺量，例如残留体积和总肺容量。这些与PFT测量的肺量密切相关。该审查评估了当前使用量化CT作为PFT中PFT的代理的证据，并讨论了CT在COPD诊断和评估中的量化模型中的挑战。为了更好地理解传统的PFT测量的相关性，并且在替换这些参数时，CT可能在替换这些参数中发挥作用，讨论了COPD病理和传统的PFT测量。

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