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首页> 外文期刊>Open Journal of Ophthalmology >The Long-Term Clinical Efficacy of Smart Plug in the Treatment of Aqueous Tear Deficiency Dry Eye: Results of a 5-Year Study
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The Long-Term Clinical Efficacy of Smart Plug in the Treatment of Aqueous Tear Deficiency Dry Eye: Results of a 5-Year Study

机译:智能插头的长期临床疗效治疗含水撕裂缺陷干眼:5年的研究结果

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摘要

Background: Dry eye syndrome, which affects 10% to 20% of adults, is a disorder of the tear film and is associated with symptoms of ocular discomfort. Smart Plug is a mechanical treatment in which the tear drainage system is blocked in order to aid in the preservation of natural tears on the ocular surface. Purpose: To evaluate the long-term clinical efficacy of Smart Plug in the treatment of aqueous tear deficiency dry eye. Patients and Methods: Retrospective study. Three hundred and two patients with aqueous tear deficiency dry eye were enrolled and all the patients accepted the punctual plug of Smart plug from Jan. 2011 to Jan. 2016. The clinical symptoms, Schirmer’s I test, Fluorescein staining (FL), tear break up time (TBUT), and complications were observed and analyzed. Results: Three hundred and two patients (604 eyes) were treated with Smart Plug (22 cases accepted upper and lower punctual plug, 280 cases only lower punctual plug). There were 109 males (36.1%) and 193 females (63.9%) with a mean age of 44.54 years old (Range from 25 to 83 years). Ten cases required the upper Smart Plug after lower punctual plug insertion because of no significantly improved symptoms. Smart plug was removed in 3 patients (1%) due to tearing. Six patients had mild postoperative tearing and no special treatment was required. Lacrimal canaliculitis occurred postoperatively in 8 cases (2.6%) (6 lower and 2 upper), and the affected plug was removed and treated with topical antibiotic eye drops. The BUT, SIT and FL scores of all patients were significantly improved from (2.11 ± 1.01, 4.20 ± 1.07, 6.06 ± 1.97) to (4.34 ± 1.22, 9.01 ± 1.56, 2.33 ± 1.28) respectively after at least 36 months of follow-up (All P < 0.01). The subjective symptoms alleviated after treatment, and the difference was statistically significant ( P < 0.05). Conclusion: During a mean follow-up of 4.3 years, Smart plug is an effective method for the treatment of aqueous tear deficiency dry eye in spite of its postoperative complications such as canaliculitis and tearing.
机译:背景:干眼症综合征影响10%至20%的成年人,是泪滴膜的疾病,与眼部不适的症状有关。智能插头是一种机械处理,其中撕裂排水系统被堵塞,以帮助保存在眼表面上的自然撕裂。目的:评价智能插头的长期临床疗效治疗水性泪滴缺陷的干眼液。患者及方法:回顾性研究。有三百患有含水泪缺乏的患者患有干眼症,所有患者从2011年1月到2016年1月,所有患者都接受了智能插头的准时插头。临床症状,奇氏症的我测试,荧光素染色(FL),撕裂分手观察并分析了时间(结核病)和并发症。结果:三百名患者(604只眼睛)用智能插头处理(22例接受上下准时的塞子,280例较低的准时插头)。有109名男性(36.1%)和193名女性(63.9%),平均年龄为44.54岁(范围为25至83岁)。在较低准时的插头插入后,需要十个案例需要较低的症状。由于撕裂,3例患者中除去智能插头(1%)。六名患者患有温和的术后撕裂,不需要特殊处理。术后8例(2.6%)(6个低,2个上部)发生泪腺炎,并用局部抗生素滴眼液除去受影响的塞子。除了36个月之后,所有患者的所有患者的静置和流量分数分别显着改善(2.11±1.01,4.07,6.06±1.56,6.01±1.56,2.33±1.28) - Up(所有P <0.01)。治疗后缓解的主观症状,差异有统计学意义(P <0.05)。结论:在平均随访4.3岁,智能插头是一种有效的方法,用于治疗水性泪滴缺乏干眼症,尽管其术后并发症如Canaliculitis和撕裂。

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