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Epidemiologic Study of the Discoid Meniscus: Investigating Demographic-Based Predictors in Large-Scale Claims Database

机译:盘状弯月面的流行病学研究:在大型索赔数据库中调查基于人口的预测因子

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Background: Discoid meniscus epidemiology remains poorly defined for race and sex, in part, due to limitations of retrospective studies and small case series. A better understanding of epidemiology may improve clinical care and diagnostic precision. Purpose: Our purpose is to better define the epidemiology of discoid meniscus by analyzing a large, national database for incidence rates by sex and race. Methods: Analysis was conducted on the national-scale Clinformatics Data Mart Database by Optum. Proportions of the database’s racial categories (Asian, Black, Hispanic, White, and Unknown) in the total population of diagnosed discoid meniscus cases (n = 1,006) were calculated and compared via chi-squared tests to the total database population (n = 65,759,970). This analysis was repeated for the population of patients who received knee arthroscopies (81,205). Incidence rates were calculated from these populations as well. Finally, a multivariable logistic regression analysis based on the population of arthroscopy-receiving patients was performed to control for age, reported gender, and income. Results: Proportions of Asian, Black, Hispanic, and White racial categories in the discoid meniscus group were 5.7%, 7.3%, 20.6%, 66.4%, respectively; the proportions of each racial category in the total population were 5.2%, 10.3%, 13.5%, 71.0%, respectively. Incidence rates (per 10,000) for these groups in the arthroscopy population were 72.9, 25.6, 49.2, 25.6, respectively. Our logistic regression model indicated that race was not a statistically significant predictor for our dataset after income adjusting. Adjusting for other covariates, the odds of a discoid meniscus diagnosis decreased by 6% for each increase in age (p & 0.001) and were 41% lower for males compared to females (p & 0.001). Conclusion : Prior studies have suggested that race (Asian and Hispanic, is a predictor of higher incidence of discoid meniscus – this study did not show a difference in incidence based upon race. Patient sex and age was identified as significant predictors for discoid meniscus, and increasing age showed a decreasing incidence of this condition. This study’s analysis of a large, national claims database allows for a comprehensive epidemiological study on this topic, offering proportions and incidence rates by race appropriate for application to the US population. Its conclusions promote patient sex and age as significant predictors and question the beliefs on race-associated incidence often based on comparing results from the corpus of single-site cohort studies.
机译:背景:由于回顾性研究和小案系列的局限性,烤盘弯月面流行病学仍然是竞争和性别的差异不足。更好地理解流行病学可能改善临床护理和诊断精度。目的:我们的目的是通过分析性别和比赛的发病率,更好地定义盘状半月板的流行病学。方法:通过OPTUM在国家规模的Clarformatics数据集市数据库上进行分析。数据库的种族类别(亚洲,黑色,西班牙裔,白色和未知)的比例计算,并通过Chi平方测试对总数据库群体进行比较并比较(n = 65,759,970 )。对于接受膝关节关节镜的患者群体重复这种分析(81,205)。发病率也从这些群体计算出来。最后,基于关节镜接收患者群体的多变量逻辑回归分析进行控制,控制年龄,报告性别和收入。结果:薯片半月板组中的亚洲,黑人,西班牙裔和白人种族类别的比例分别为5.7%,7.3%,20.6%,66.4%;总人口中每个种族类别的比例分别为5.2%,10.3%,13.5%,71.0%。关节镜检查中这些组的发病率(每10,000个)分别为72.9,25.6,49.2,25.6。我们的Logistic回归模型表明,在收入调整后,竞赛对我们的数据集没有统计上重要的预测因子。调整其他协变量,每次年龄(P& 0.001)的每增加增加的液体弯月面诊断的几率降低了6%,与女性相比,男性的41%降低(P& 0.001)。结论:事先研究表明,种族(亚洲和西班牙裔人是一种令人难以置信的椎间盘突出态度的预测因素 - 本研究没有展示基于比赛的发病率差异。患者性和年龄被确定为表现出色半月板的重要预测因子,而且增加的年龄显示这种情况的发生率降低。本研究对大型国家索赔数据库的分析允许对这一主题进行全面的流行病学研究,通过适合应用于美国人群的比赛提供比例和发病率。其结论促进患者性行为和年龄作为重要的预测因子,并质疑种族相关发病率的信念,通常基于单位队列研究语料的结果。

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