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首页> 外文期刊>The Journal of automatic chemistry >Diagnostic Fragment-Ion-Based for Rapid Identification of Chlorogenic Acids Derivatives in Inula cappa Using UHPLC-Q-Exactive Orbitrap Mass Spectrometry
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Diagnostic Fragment-Ion-Based for Rapid Identification of Chlorogenic Acids Derivatives in Inula cappa Using UHPLC-Q-Exactive Orbitrap Mass Spectrometry

机译：诊断片段离子离子基于UHPLC-Q-辐射锻体质谱法快速鉴定内部氨基酸衍生物的衍生物

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Inula cappa (Buch.-Ham. ex D. Don) DC has been used in traditional Chinese medicine to treat malaria, dysentery, and hepatitis. Previous studies have shown that chlorogenic acid is the effective ingredient of plants in this family. And the research of the chlorogenic acid in Inula cappa will help to further improve the effective resource utilization rate of this plant. Therefore, it is necessary to establish an accurate method to characterize the chlorogenic acid components in Inula cappa . In this study, a simple, fast, and sensitive UHPLC-Q-Exactive Orbitrap mass spectrometry method was established, which can simultaneously analyze known and unknown ingredients in a short time (within 30 minutes) in Inula cappa. According to the diagnosis fragmentation ions, retention time, and bibliography, 68 chlorogenic acid derivatives were identified in Inula cappa . The results of this experiment lay the foundation for the active substances and quality control of Inula cappa and provide a theoretical basis for whether Inula cappa can be an alternative to the endangered wild medicinal materials of the same family.
机译：Inula Cappa（Buch.-Ham。ex D. Don）DC已用于中药治疗疟疾，痢疾和肝炎。以前的研究表明，绿原酸是该家族植物的有效成分。在内拉卡帕对绿原酸的研究将有助于进一步提高该植物的有效资源利用率。因此，需要建立一种准确的方法来表征内部癌症中的绿色酸组分。在该研究中，建立了一种简单，快速，敏感的UHPLC-Q-辐射露体积法，其可以在InulaCappa的短时间内分析已知和未知成分（30分钟内）。根据诊断碎片离子，保留时间和参考书目，在Inula Cappa中鉴定了68个鲜lAllencatic酸衍生物。该实验的结果为Inula Cappa的活性物质和质量控制奠定了基础，为Inula Cappa提供了濒危野生药物的替代品的理论依据。

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